Gianna Cai
7 Papers
Gianna Cai is an academic researcher. The author has contributed to research in topics: Medicine & Outbreak. The author has an hindex of 1, co-authored 3 publications.
Chat about Author
Papers
Mpox vaccine and infection-driven human immune signatures: an immunological analysis of an observational study.
Nathan Bloom,Gianna Cai,Jordan J. Clark,Alison Tarke,Maria Bermudez-Gonzalez,Deena R. Altman,Luz Amarilis Lugo,Francisco Pereira Lobo,Wenlin Ren,Lili Qin,Jennifer L. Yates,Danielle Hunt,William T. Lee,Shane Crotty,Florian Krammer,Alba Grifoni,Alessandro Sette,Viviana Simon,Camila H. Coelho +18 more
- 17 Jul 2023
TL;DR: Infection with monkeypox virus resulted in robust B-cell and T- cell responses, whereas immunisation with JYNNEOS elicited more robust T-cell responses, which can help to inform vaccine design and policies for preventing mpox in humans.
35
Kinetics and durability of humoral responses to SARS-CoV-2 infection and vaccination
Komal Srivastava,Juan Manuel Carreño,C. Gleason,Brian C. Monahan,Gagandeep Singh,Anass Abbad,J. Tcheou,A. Raskin,Giulio Kleiner,H. Bakel,Emilia Mia Sordillo,Paris Study Group,Florian Krammer,Viviana Simon,Hala Alshammary,Angela Amoako,Dalles Andre,Mahmoud Awawda,Maria Bermudez-Gonzalez,K. Beach,D. Bielak,Gianna Cai,Rachel Chernet,Christian Cognigni,Yuexing Chen,Lily Q. Eaker,E Ferreri,D. Floda,Miriam Fried,Joshua Hamburger,Denise Jurczyszak,Hyun Min Kang,N. A. Lyttle,J. Matthews,Jacob Mauldin,W. Mendez,Jacob Mischka,S Morris,CF Lubbertus,Ismail Mulder,Jessica Nabeel,A. Nardulli,Kayla T Oostenink,Ashley-Beathrese Russo,Miti S Salimbangon,Amber A Saksena,Levy A Shin,Daniel Sominsky,Leeba Stadlbauer,Morgan D. Sullivan,Temima Van Kesteren,A. Yellin,Wajnberg +52 more
TL;DR: This study provides strong evidence for the fact that SARS-CoV-2 antibody responses are long lasting, with an initial waning phase followed by a stabilization phase.
3
SARS-CoV-2 vaccination induces mucosal antibody responses in previously infected individuals
Kaori Sano,Disha Bhavsar,Gagandeep Singh,D. Floda,Komal Srivastava,C. Gleason,Angela Amoako,Dalles Andre,K. Beach,Maria Bermudez-Gonzalez,Gianna Cai,Christian Cognigni,H. Kawabata,Giulio Kleiner,N. A. Lyttle,W. Mendez,Lubbertus C. F. Mulder,Annika Oostenink,A. Raskin,A.A. “Sonny” Rooker,Kayla T. Russo,A. Salimbangon,Miti Saksena,L. Sominsky,J. Tcheou,Ania Wajnberg,Juan Manuel Carreño,Viviana Simon,Florian Krammer +28 more
TL;DR: In this paper , the authors analyzed paired serum and saliva samples from patients with and without prior coronavirus disease 2019 (COVID-19) at multiple time points pre and post severe acute respiratory syndrome coronavalirus 2 (SARS-CoV-2) mRNA vaccination.
Cellular mechanisms associated with sub-optimal immune responses to SARS-CoV-2 bivalent booster vaccination in patients with Multiple Myeloma.
Adolfo Aleman,Morgan van Kesteren,Ariel Kogan Zajdman,K. Srivastava,Christian Cognigni,Jacob Mischka,Lucia Y. Chen,Bhaskar Upadhyaya,Kseniya Serebryakova,J. R. Nardulli,N. A. Lyttle,Katerina Kappes,Hayley Jackson,C. Gleason,Annika Oostenink,Gianna Cai,Oliver Van Oekelen,Harm van Bakel,Emilia Mia Sordillo,Carlos Cordon-Cardo,Miriam Merad,Sundar Jagannath,Ania Wajnberg,Viviana Simon,Samir Parekh,Hala Alshammary,Dalles Andre,Radhika N. Banu,K. Beach,Maria Bermudez-Gonzalez,Ajai Chari,Yuexing Chen,Hearn Cho,Adolfo Firpo,Ana S. Gonzalez-Reiche,Eun Hye Kim,Giulio Kleiner,Florian Krammer,Jacob Mauldin,Rao Mendu,Brian Monahan,Shambavi Richard,Joshua Richter,Cesar Rodriguez,Adrianna Rossi,A. Salimbangon,Laryssa Sanchez,Daniel Verina +47 more
TL;DR: It is found that bivalent vaccination provides significant boost in protection to the omicron variant in patients with Multiple Myeloma, in a treatment specific manner.
Development of a novel serological assay for the detection of mpox infection in vaccinated populations.
Jennifer L. Yates,Danielle Hunt,Karen E. Kulas,Karen J. Chave,Linda Styer,Sandhya T. Chakravarthi,Gianna Cai,Maria Bermudez-Gonzalez,Giulio Kleiner,Deena R. Altman,K. Srivastava,Viviana Simon,Dennis Feihel,Joseph McGowan,Wayne Hogrefe,P Noone,Christina Egan,Mark K. Slifka,William T. Lee +18 more
TL;DR: A high‐throughput multiplex microsphere immunoassay using a combination of mpox‐specific peptides and cross‐reactive OPV proteins that results in the specific serologic detection of mpx infection with 93% sensitivity and 98% specificity is developed.