Giancarlo Castaman
University of Florence
435 Papers
3.6K Citations
Giancarlo Castaman is an academic researcher from University of Florence. The author has contributed to research in topics: Medicine & Von Willebrand disease. The author has an hindex of 60, co-authored 389 publications. Previous affiliations of Giancarlo Castaman include UniFi & University of Milan.
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Papers
Desmopressin-induced thrombocytopenia in type I platelet discordant von Willebrand disease
TL;DR: Cases indicate that after DDAVP thrombocytopenia can occur in vWD other than type IIB, and this occurrence in a 39 year old male and his son with phenotypic characteristics of type I vWD, 'platelet discordant subtype' is described.
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Cancers in Patients with von Willebrand Disease: A Survey from the Italian Association of Haemophilia Centres
Massimo Franchini,Caterina Di Perna,Cristina Santoro,Giancarlo Castaman,Simona Maria Siboni,Ezio Zanon,Silvia Linari,Paolo Gresele,Samantha Pasca,Antonio Coppola,Rita Santoro,Mariasanta Napolitano,Paola Ranalli,Annarita Tagliaferri +13 more
TL;DR: A retrospective study on cancers among Italian patients with von Willebrand disease (VWD) finds that a substantial number of cancers are recorded among VWD patients and that these patients are safely managed by HTC physicians through a multidisciplinary approach.
Erythema multiforme after intravenous immunoglobulin.
TL;DR: A woman with idiopathic thrombocytopenic purpura not responsive to corticosteroids was infused with 400 mg/Kg/day of pH 4/pepsin-treated immunoglobulin (Sandoglobulus, Sandoz) for 5 days with rapid normalization of platelet count, and a case of severe erythema multiforme (EM) developing during this treatment is reported.
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The A20210 allele in the prothrombin gene enhances the risk of venous thrombosis in carriers of inherited protein S deficiency.
TL;DR: The presence of the prothrombin mutation seems to increase the risk of VT in carriers of protein S deficiency, although additional families are required to fully estimate the magnitude of risk.
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Blood group significantly influences von Willebrand factor increase and half-life after desmopressin in von Willebrand disease Vicenza.
TL;DR: The codon 620tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene isamajordeterminant ofGravesDisease is associated with SLE independently of the association of PDCD1.
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