Gert Van Peer
Ghent University
20 Papers
282 Citations
Gert Van Peer is an academic researcher from Ghent University. The author has contributed to research in topics: Biology & Neuroblastoma. The author has an hindex of 13, co-authored 19 publications. Previous affiliations of Gert Van Peer include Ghent University Hospital.
Chat about Author
Papers
The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in Neuroblastoma
Pieter Mestdagh,Anna-Karin Boström,Francis Impens,Erik Fredlund,Erik Fredlund,Gert Van Peer,Pasqualino De Antonellis,Kristoffer von Stedingk,Bart Ghesquière,Stefanie Schulte,Michael Dews,Andrei Thomas-Tikhonenko,Johannes H. Schulte,Massimo Zollo,Alexander Schramm,Kris Gevaert,Håkan Axelson,Franki Speleman,Jo Vandesompele +18 more
TL;DR: In this paper, the miR-17-92 microRNA cluster is often activated in cancer cells, but the identity of its targets remains elusive, and the effects of activation of the microRNA clusters on global protein expression in neuroblastoma (NB) cells are examined.
312
The need for transparency and good practices in the qPCR literature
Stephen A. Bustin,Vladimir Benes,Jeremy A. Garson,Jan Hellemans,Jim F. Huggett,Mikael Kubista,Reinhold Mueller,Tania Nolan,Michael W. Pfaffl,Gregory L. Shipley,Carl T. Wittwer,Peter Schjerling,Philip J. R. Day,Mónica Abreu,Begoña Aguado,Jean-François Beaulieu,Anneleen Beckers,Sara Bogaert,John A. Browne,Fernando Carrasco-Ramiro,Liesbeth Ceelen,Kate L. Ciborowski,Pieter Cornillie,Stephanie Coulon,Ann Cuypers,Sara De Brouwer,Leentje De Ceuninck,Jurgen De Craene,Hélène De Naeyer,Ward De Spiegelaere,Kato Deckers,Annelies Dheedene,Kaat Durinck,Margarida Ferreira-Teixeira,Annelies Fieuw,Jack M. Gallup,Sandra Gonzalo-Flores,Karen Goossens,Femke Heindryckx,Elizabeth Herring,Hans Hoenicka,Laura Icardi,Rolf Jaggi,Farzad Javad,Michael Karampelias,Frederick S. B. Kibenge,Molly J. T. Kibenge,Candy Kumps,Irina Lambertz,Tim Lammens,Amelia Markey,Peter Messiaen,Evelien Mets,Sofia Morais,Alberto Mudarra-Rubio,Justine K. Nakiwala,Hilde Nelis,Pål A. Olsvik,Claudina Perez-Novo,Michelle Plusquin,Tony Remans,Ali Rihani,Paulo Rodrigues-Santos,Pieter Rondou,Rebecca Sanders,Katharina Schmidt-Bleek,Kerstin Skovgaard,Karen Smeets,Laura Tabera,Stefan Toegel,Tim Van Acker,Wim Van den Broeck,Joni Van der Meulen,Mireille Van Gele,Gert Van Peer,Mario Van Poucke,Nadine Van Roy,Sarah Vergult,Joris Wauman,Marina Tshuikina-Wiklander,Erik Willems,Sara Zaccara,Fjoralba Zeka,Jo Vandesompele +83 more
TL;DR: Two surveys of over 1,700 publications whose authors use quantitative real-time PCR (qPCR) reveal a lack of transparent and comprehensive reporting of essential technical information.
285
The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma
Pieter Mestdagh,Ana-Karin Bostrom,Francis Impens,Erik Fredlund,Gert Van Peer,Paquito De Antonelis,Kristoffer von Stedingk,Bart Ghesquière,Stefanie Schulte,Michael Dews,Andrei Thomas-Tikhonenko,Johannes H. Schulte,Massimo Zollo,Alexander Schramm,Kris Gevaert,Hakan Axelsons,Franki Speleman,Jo Vandesompele +17 more
- 01 Jan 2011
TL;DR: It is shown that miR-17-92 is a potent inhibitor of TGF-β signaling by functioning both upstream and downstream of pSMAD2, and triggers downregulation of multiple key effectors along the TGF -β signaling cascade as well as direct inhibition of T GF-β-responsive genes.
252
Identification of miR-145 as a key regulator of the pigmentary process
Peter Dynoodt,Pieter Mestdagh,Gert Van Peer,Jo Vandesompele,Karen Goossens,Luc Peelman,Barbara Geusens,Reinhart Speeckaert,Jo Lambert,Mireille Van Gele +9 more
TL;DR: An miRNA signature associated with forskolin and ssUV treatment is established and the significant down- or upregulation of major pigmentation genes, after modulating miR-145 expression, suggests a key role for mi R-145 in regulating melanogenesis.
103
Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers.
Anneleen Decock,Maté Ongenaert,Jasmien Hoebeeck,Jasmien Hoebeeck,Katleen De Preter,Gert Van Peer,Wim Van Criekinge,Ruth Ladenstein,Johannes H. Schulte,Rosa Noguera,Raymond L. Stallings,Raymond L. Stallings,An Van Damme,Genevieve Laureys,Joëlle Vermeulen,Tom Van Maerken,Tom Van Maerken,Frank Speleman,Jo Vandesompele +18 more
TL;DR: In this article, the authors applied two independent genome-wide methylation screening methodologies to eight neuroblastoma cell lines to identify prognostic tumor DNA methylation biomarkers, which yielded 43 candidate biomarkers that were subsequently tested by high-throughput methylation-specific PCR.
80