Gerhard Klein
Hoffmann-La Roche
10 Papers
117 Citations
Gerhard Klein is an academic researcher from Hoffmann-La Roche. The author has contributed to research in topics: Renal function & Creatinine. The author has an hindex of 8, co-authored 10 publications.
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Papers
Determination of reference intervals for serum creatinine, creatinine excretion and creatinine clearance with an enzymatic and a modified Jaffé method.
TL;DR: The reference interval for the entire group was found to be 66-143 ml/minute with the enzymatic assay and 71-151 ml/min with the chemical one, and showed no gender difference in contrast to some previous studies.
252
Reference Intervals for Serum Creatinine Concentrations: Assessment of Available Data for Global Application
Ferruccio Ceriotti,James C. Boyd,Gerhard Klein,Joseph Henny,J. M. Queralto,Veli Kairisto,Mauro Panteghini,Decision Limits +7 more
TL;DR: Reference intervals for serum creatinine remain relevant despite the current emphasis on the use of the estimated glomerular filtration rate (GLR) for assessing renal function.
•Journal Article
Evaluation of a new alpha-amylase assay using 4.6-ethylidene-(G7)-1-4-nitrophenyl-(G1)-alpha-D-maltoheptaoside as substrate.
J. D. Kruse-Jarres,C. Kaiser,J. C. M. Hafkenscheid,W. Hohenwallner,W. Stein,J. Bohner,Gerhard Klein,W. Poppe,E. Rauscher +8 more
TL;DR: The determination of alpha-amylase activity using an ethylidene-blocked 4-nitrophenyl-maltoheptaoside (EPS) has been evaluated in five laboratories on eight different analysers and the present method is equal or better with respect to the imprecision, linearity and interlaboratory transferability of results in human and control sera.
66
Pediatric reference intervals determined in ambulatory and hospitalized children and juveniles.
TL;DR: The results confirm in most cases the typical age concentration relationship of the measured quantities documented for similar methods but in some critical cases, in particular for sTfR and ferritin, the study produces limits which differ distinctly from those earlier reported.
29
Reference Ranges for α-Amylase in Serum and Urine with 4,6-Ethylidene-(G7)-1-4-nitrophenyl-(G1)-α,D-maltoheptaoside as Substrate
W. Hohenwallner,W. Stein,J. C. M. Hafkenscheid,J. D. Kruse-Jarres,C. Kaiser,A. Hubbuch,Gerhard Klein +6 more
TL;DR: Reference ranges for alpha-amylase in serum, spontaneously voided urine, and 24-hour urine were determined, using 4,6-ethylidene-(G7)-1-4-nitrophenyl-(Gl)-alpha,D-maltoheptaoside as the substrate (EPS method), at 25, 30, and 37 degrees C as mentioned in this paper.