Gerd A. Kullak-Ublick
University of Zurich
256 Papers
1.4K Citations
Gerd A. Kullak-Ublick is an academic researcher from University of Zurich. The author has contributed to research in topics: Medicine & Bile acid. The author has an hindex of 61, co-authored 245 publications. Previous affiliations of Gerd A. Kullak-Ublick include Novartis & National Patient Safety Foundation.
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Papers
Fc gamma receptor CD64 modulates the inhibitory activity of infliximab.
Kacper A. Wojtal,Gerhard Rogler,Michael Scharl,Luc Biedermann,Pascal Frei,Michael Fried,Achim Weber,Jyrki J. Eloranta,Gerd A. Kullak-Ublick,Stephan R. Vavricka +9 more
TL;DR: CD64 modulates the efficacy of infliximab both in vitro and ex vivo, whereas the presence of this receptor has no impact on the inhibitory activity of certolizumab-pegol, which lacks Fc fragment.
3.5 Clinical Decision Support Systems
Gerd A. Kullak-Ublick,Timo Siepmann,Wilhelm Kirch +2 more
- 01 Jan 2012
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Intestinal expression of cytochrome P450 enzymes and ABC transporters and carbamazepine and phenytoin disposition
C. Simon,Bruno Stieger,Gerd A. Kullak-Ublick,Michael Fried,Susanne G. Mueller,Jean-Marc Fritschy,Heinz Gregor Wieser,Christiane Pauli-Magnus +7 more
TL;DR: Interindividual variability in intestinal absorption and bioavailability might contribute to inadequate control of seizures under treatment with carbamazepine and phenytoin and therefore intestinal expression levels and genetics of CYP3A4, CYP2C9/19, MDR1 and MRP2 are correlated.
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Hepatocyte Nuclear Factor (HNF) 1 and HNF4 Mediate Hepatic Multidrug Resistance Protein 2 Up-Regulation during Hepatitis C Virus Gene Expression
TL;DR: It is reported that a homeodomain-containing transcription factor, hepatocyte nuclear factor (HNF) 1, plays a central role in liver gene regulation during HCV gene expression and/or subgenome replication and may constitute, in part, the cellular detoxification task force duringHCV infection.
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Thermoplasmonic-Assisted Cyclic Cleavage Amplification for Self-Validating Plasmonic Detection of SARS-CoV-2.
Guangyu Qiu,Zhibo Gai,Lanja Saleh,Jiukai Tang,Ting Gui,Gerd A. Kullak-Ublick,Jing Wang,Jing Wang +7 more
TL;DR: In this article, a thermoplasmonic-assisted dual-mode transducing (TP-DMT) concept was presented, where an amplification-free-based direct viral RNA detection and an amplificationbased cyclic fluorescence probe cleavage (CFPC) detection collaborated to provide a sensitive and self-validating plasmonous nanoplatform for quantifying trace amounts of SARS-CoV-2 within 30 min.
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