Gerard J. Criner
Temple University
675 Papers
2K Citations
Gerard J. Criner is an academic researcher from Temple University. The author has contributed to research in topics: Medicine & COPD. The author has an hindex of 73, co-authored 541 publications. Previous affiliations of Gerard J. Criner include University of North Carolina at Chapel Hill & Queen Elizabeth Hospital Birmingham.
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Papers
Lack of Effect of Oral Sulforaphane Administration on Nrf2 Expression in COPD: A Randomized, Double-Blind, Placebo Controlled Trial
Robert A. Wise,Janet T. Holbrook,Gerard J. Criner,Sanjay Sethi,Sobharani Rayapudi,Kuladeep Sudini,Elizabeth A. Sugar,Alyce E. Burke,Rajesh K. Thimmulappa,Anju Singh,Paul Talalay,Jed W. Fahey,Charles S. Berenson,Michael R. Jacobs,Shyam Biswal +14 more
TL;DR: Sulforaphane administered for four weeks at doses of 25 μmoles and 150μmoles to patients with COPD did not stimulate the expression of Nrf2 target genes or have an effect on levels of other anti-oxidants or markers of inflammation.
Predicting response to benralizumab in chronic obstructive pulmonary disease: analyses of GALATHEA and TERRANOVA studies.
Gerard J. Criner,Bartolome R. Celli,Dave Singh,Alvar Agusti,Alberto Papi,Maria Jison,Natalya Makulova,Vivian H. Shih,Laura Brooks,Peter Barker,Ubaldo J. Martin,Paul Newbold +11 more
TL;DR: Elevated blood eosinophil counts combined with clinical characteristics identified a subpopulation of patients with COPD who had reductions in exacerbations with benralizumab treatment and identified the potential efficacy of benralIZumab 100 mg for this subpopulation.
102
DNA methylation profiling in human lung tissue identifies genes associated with COPD.
Jarrett D. Morrow,Michael H. Cho,Craig P. Hersh,Victor Pinto-Plata,Bartolome R. Celli,Nathaniel Marchetti,Gerard J. Criner,Raphael Bueno,George R. Washko,Kimberly Glass,Augustine M.K. Choi,John Quackenbush,Edwin K. Silverman,Dawn L. DeMeo +13 more
TL;DR: Enrichment for genes implicated in asthma and lung function and for transcription factors suggests the potential pathogenic relevance of genes identified through differential methylation and the intersection with a broader range of GWAS associations.
99
Cardiac function in sickle cell anemia
TL;DR: Increased preload and decreased afterload compensate for the LV dysfunction and maintain a normal ejection fraction and high cardiac output in patients with SCA.
98
Anxiety is associated with diminished exercise performance and quality of life in severe emphysema: a cross-sectional study
Nicholas D. Giardino,Jeffrey L. Curtis,Adin Cristian Andrei,Vincent S. Fan,Joshua O. Benditt,Mark Lyubkin,Keith S. Naunheim,Gerard J. Criner,Barry J. Make,Robert A. Wise,Susan K. Murray,Alfred P. Fishman,Frank C. Sciurba,Israel Liberzon,Fernando J. Martinez +14 more
TL;DR: In clinically stable patients with moderate to severe emphysema, anxiety is associated with worse exercise performance, quality of life and shortness of breath, after accounting for the influence of demographic and physiologic factors known to affect these outcomes.