Gerard Devitt
German Cancer Research Center
3 Papers
34 Citations
Gerard Devitt is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Antigen & Vimentin. The author has an hindex of 3, co-authored 3 publications.
Chat about Author
Papers
Generation of RAGE-1 and MAGE-9 peptide-specific cytotoxic T-lymphocyte lines for transfer in patients with renal cell carcinoma.
Nicole Oehlrich,Gerard Devitt,Michael Linnebacher,Yvette Schwitalle,Sonja Grosskinski,Stefan Stevanovic,Margot Zöller,Margot Zöller +7 more
TL;DR: B cells are well suited as APCs for the generation of large numbers of tumor peptide‐specific CTLs for adoptive transfer and MAGE‐9 as well as RAGE‐1 may well provide suitable targets for immunotherapy of RCC.
36
Serological analysis of human renal cell carcinoma
Gerard Devitt,Christiane Meyer,Nicole Wiedemann,Stefan B. Eichmüller,Annette Kopp-Schneider,Axel Haferkamp,Richard E. Hautmann,Margot Zöller,Margot Zöller +8 more
TL;DR: Serological analysis of cDNA expression libraries (SEREX) has proven to be a useful technique in the quest to elucidate the repertoire of immunogenic gene products in human cancer, and the method was applied to human renal cell carcinoma (RCC) in order to identify associated immunogenic genes products.
Identification of human renal cell carcinoma associated genes by suppression subtractive hybridization.
M. J.J.G. Stassar,Gerard Devitt,M. Brosius,L. Rinnab,J. Prang,T. Schradin,J. Simon,S. Petersen,Annette Kopp-Schneider,Margot Zöller,Margot Zöller +10 more
TL;DR: 14 differentially expressed genes, only 6 of which have previously been associated with RCC, are related to tumour growth/survival, and since some of these genes were overexpressed in 80–90% of RCC tissues, it is important to evaluate their suitability as therapeutic targets.