Gerald Marks
Thomas Jefferson University
23 Papers
274 Citations
Gerald Marks is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Rectum & Radiation therapy. The author has an hindex of 9, co-authored 23 publications. Previous affiliations of Gerald Marks include Thomas Jefferson University Hospital.
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Papers
Preoperative chemoradiation in fixed distal rectal cancer: dose time factors for pathological complete response.
Mohammed Mohiuddin,William F. Regine,William J. John,Patrick F. Hagihara,Patrick C. McGrath,Daniel E. Kenady,Gerald Marks +6 more
TL;DR: Dose intensity of 5-FU and dose of radiation correlate significantly with the likelihood of achieving a pCR, and a preoperative radiation dose of 5500 cGy or higher can achieve pCR rates of approximately 50%, even in fixed cancers of the rectum.
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Cloacogenic carcinoma of the anorectum in homosexual men: an observation of four cases.
Harry S. Cooper,Harry S. Cooper,Arthur S. Patchefsky,Arthur S. Patchefsky,Gerald Marks,Gerald Marks +5 more
TL;DR: The realization that the anorectal transitional zone shares a common embryologic origin with the uterine cervix, a site of cancer long known to be associated with factors related to sexual intercouse, leads to the serious question of the etiologic potential of receptive anal intercourse in the development of cloacogenic carcinoma.
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Laparoscopic transanal abdominal transanal resection with sphincter preservation for rectal cancer in the distal 3 cm of the rectum after neoadjuvant therapy
TL;DR: The study results indicate excellent local recurrence (2.7%) and 5-year survival rates without the need for permanent colostomy in patients with cancers in the distal one-third of the rectum in patients treated with laparoscopic TATA after neoadjuvant therapy.
94
Redefining contraindications to laparoscopic colorectal resection for high-risk patients
TL;DR: Better than expected outcomes in this patient population reinforce the benefits of minimally invasive surgery for this patient group and argues against using parameters of increased age, morbid obesity, high ASA class, or preoperative radiation alone as contraindications to even complex laparoscopic colorectal procedures.
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Preoperative radiation therapy and sphincter preservation by the combined abdominotranssacral technique for selected rectal cancers.
TL;DR: Preliminary results indicate that full dose preoperative radiation therapy for selected unfavorable and low level cancers permits safe and effective sphincter preservation surgery by the combined abdominotranssacral technique.
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