Georgios Chrysofakis
University of Crete
7 Papers
208 Citations
Georgios Chrysofakis is an academic researcher from University of Crete. The author has contributed to research in topics: COPD & Sputum. The author has an hindex of 6, co-authored 7 publications.
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Papers
Nitrosative Stress, Heme Oxygenase-1 Expression and Airway Inflammation During Severe Exacerbations of COPD
TL;DR: The hypothesis of an involvement of inflammatory and nitrosative stress in severe COPD exacerbations is supported and future therapeutic strategies may aim at regulating inflammation and NO synthesis during COPD exacerbateations.
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Induced sputum CD8+ T-lymphocyte subpopulations in chronic obstructive pulmonary disease.
Nikolaos Tzanakis,Georgios Chrysofakis,Maria Tsoumakidou,D. Kyriakou,Joanna Tsiligianni,Demosthenes Bouros,Nikolaos M. Siafakas +6 more
TL;DR: An imbalance both in T-lymphocyte subpopulation (CD4/CD8) and in CD8+ cell subsets (Tc1/Tc2) characterizes the inflammatory responses of smokers with established COPD.
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Changes in sputum T-lymphocyte subpopulations at the onset of severe exacerbations of chronic obstructive pulmonary disease.
TL;DR: It is concluded that a CD8+ve type-2-mediated immune response is induced at the onset of severe COPD exacerbation through analysis of sputum.
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Is there any correlation between the ATS, BTS, ERS and GOLD COPD's severity scales and the frequency of hospital admissions?
Maria Tsoumakidou,Nikolaos Tzanakis,Olga Voulgaraki,Ioanna Mitrouska,Georgios Chrysofakis,Maria Samiou,Nikolaos M. Siafakas +6 more
TL;DR: In conclusion the GOLD and ERS classification systems of severity of COPD correlated to exacerbations causing hospitalisation but the same was not true for the ATS and BTS severity scales.
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Inflammatory cell profiles and T-lymphocyte subsets in chronic obstructive pulmonary disease and severe persistent asthma.
TL;DR: A large number of patients with severe persistent asthma and chronic obstructive pulmonary disease are diagnosed with non‐reversible airflow limitation and airway neutrophilia, and the use of statins to treat these conditions is recommended.
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