George Chennell
King's College London
15 Papers
45 Citations
George Chennell is an academic researcher from King's College London. The author has contributed to research in topics: Neuroligin & Biology. The author has an hindex of 3, co-authored 8 publications.
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Papers
Planar Airy beam light-sheet for two-photon microscopy.
Neveen A. Hosny,James A. Seyforth,Gunnar Spickermann,Thomas J. Mitchell,Pedro Almada,Robert A. Chesters,Scott J. Mitchell,George Chennell,Anthony C. Vernon,Kwangwook Cho,Deepak Srivastava,Robert Forster,Tom Vettenburg +12 more
TL;DR: In this paper, a planar light-sheet was constructed from the curved propagation-invariant Airy beam, and the resulting symmetric light sheet excites two-photon fluorescence uniformly across an extended field-of-view without the need for deconvolution.
A planar Airy beam light-sheet for two-photon microscopy
Neveen A. Hosny,James A. Seyforth,Gunnar Spickermann,Thomas J. Mitchell,Pedro Almada,Robert A. Chesters,Scott J. Mitchell,George Chennell,Anthony C. Vernon,Kwangwook Cho,Deepak Srivastava,Robert J. Forster,Tom Vettenburg +12 more
TL;DR: It is shown how a planar light-sheet can be formed from the curved propagation-invariant Airy beam, and the resulting symmetric light sheet excites two-photon fluorescence uniformly across an extended field ofview without the need for deconvolution.
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Application of Airy beam light sheet microscopy to examine early neurodevelopmental structures in 3D hiPSC-derived human cortical spheroids
Dwaipayan Adhya,Dwaipayan Adhya,George Chennell,James A. Crowe,Eva P. Valencia-Alarcón,James A. Seyforth,Neveen A. Hosny,Marina V. Yasvoina,Robert Forster,Simon Baron-Cohen,Anthony C. Vernon,Deepak Srivastava +11 more
TL;DR: In this paper, an Airy-beam light sheet microscope (ALSM) was used to acquire high resolution volumetric images of internal structures within human cortical spheroids representative of early developmental time points.
Aryl hydrocarbon receptor utilises cellular zinc signals to maintain the gut epithelial barrier.
Xiuchuan Lucas Hu,Wenfeng Xiao,Yu Lei,Adam Green,Xinyi Lee,Muralidhara Rao Maradana,Xueru Xie,Rui Wang,George Chennell,M. A. Basson,Pete Kille,Wolfgang Maret,Gavin A Bewick,Yufeng Zhou,Christer Hogstrand +14 more
TL;DR: The data show that AHR activation by plant-derived dietary ligands improves gut barrier function at least partly via zinc-dependent cellular pathways, suggesting that combined dietary supplementation with AHR ligands and zinc might be effective in preventing inflammatory gut disorders.
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Neuroligin-3 and Neuroligin-4X form Nanoscopic clusters and regulate growth cone organization and size.
Nicholas J.F. Gatford,P J Michael Deans,Rodrigo R.R. Duarte,George Chennell,Katherine J. Sellers,Pooja Raval,Deepak Srivastava +6 more
TL;DR: In this article, a super-resolution microscopy revealed that NLGN3/4X clustering induced growth cone enlargement and influenced actin filament organization, and these morphological effects were not induced by autism spectrum disorder (ASD)-associated neuroligin-4X variants.
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