Geoffrey Grant
Salk Institute for Biological Studies
15 Papers
477 Citations
Geoffrey Grant is an academic researcher from Salk Institute for Biological Studies. The author has contributed to research in topics: Anterior pituitary & Luteinizing hormone. The author has an hindex of 10, co-authored 15 publications.
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Papers
TRF and Thyroid Hormones on Prolactin Secretion By Rat Anterior Pituitary Cells in Vitro
TL;DR: The effect of pGlu-His-Pro-NH2 (TRF) on the secretion of prolactin (PRL) from rat anterior pituitary glands and cell cultures derived from normal and propylthiouracil (PTU)-fed rats is reported.
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Interaction of thyrotropin releasing factor with membrane receptors of pituitary cells.
TL;DR: The binding is saturable with respect to 3H-TRF under the conditions used and stoichiometrically competible by unlabelled TRF providing the basis for a workable in vitro assay for this releasing factor.
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Characteristics of the Pituitary Binding Sites for Thyrotropin—Releasing Factor
TL;DR: An analysis of the competition binding data shows that the two binding sites on pituitary thyrotrophs have slightly different structural preference for some of the TRF analogues.
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Pituitary binding sites for [3H]-labelled luteinizing hormone releasing factor (LRF)
TL;DR: Normal rat anterior pituitary cells in culture possess two binding sites for LRF, one of which corresponds to the half-maximal biological potency of LRF and the other has low affinity and an enormously higher capacity to bind LRF.
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