Geoffrey A. Donnan
Royal Melbourne Hospital
814 Papers
6.6K Citations
Geoffrey A. Donnan is an academic researcher from Royal Melbourne Hospital. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 115, co-authored 758 publications. Previous affiliations of Geoffrey A. Donnan include Alfred Hospital & Harvard University.
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Papers
Pathophysiological determinants of worse stroke outcome in atrial fibrillation.
Hans T.H. Tu,Bruce C.V. Campbell,Soren Christensen,Marnie Collins,Deidre A De Silva,Kenneth Butcher,Mark W Parsons,Patricia Desmond,P. Alan Barber,Christopher R Levi,Christopher F. Bladin,Geoffrey A. Donnan,Stephen M. Davis,Echoplanar Imaging Thrombolytic Evaluation Trial (Epithet) Investigators +13 more
TL;DR: This study suggests that the adverse effect of AF is due to greater volumes of more severely hypoperfused tissue, leading to larger infarct size and greater risk of severe hemorrhagic transformation.
•Journal Article
Thrombolysis in acute ischemic stroke: controlled trials and clinical experience.
Werner Hacke,Thomas G. Brott,Louis R. Caplan,Dieter Meier,Cesare Fieschi,R. von Kummer,Geoffrey A. Donnan,W.-D. Heiss,Nils Wahlgren,Matthias Spranger,Gudrun Boysen,John R. Marler +11 more
TL;DR: An analysis of the risk/benefit profile of rtPA therapy based on the results of these three trials indicates that the treatment is effective and, when administered within 3 hours of symptom onset at a dose of 0.9 mg/kg, the benefits by far outweigh the risks for eligible patients.
Endovascular therapy for ischemic stroke: Save a minute—save a week
TL;DR: The patient lifetime benefits gained from reduced delays in endovascular therapy for acute ischemic stroke are quantified to show how services need to be optimized to reduce delays to endov vascular therapy.
Comparative Analysis of Markers of Mass Effect after Ischemic Stroke.
Ann-Christin Ostwaldt,Thomas W.K. Battey,Hannah J Irvine,Bruce C.V. Campbell,Bruce C.V. Campbell,Stephen M. Davis,Geoffrey A. Donnan,W. Taylor Kimberly +7 more
TL;DR: This study targeted a population with moderately sized strokes and compared midline shift to other imaging markers and determined their ability to predict long‐term outcome.
Global coagulation assays in patients with diabetes mellitus.
Hui Yin Lim,Hui Yin Lim,Brandon Lui,Mark Tacey,Mark Tacey,Anna Kwok,Suresh Varadarajan,Geoffrey A. Donnan,Harshal Hanumant Nandurkar,Prahlad Ho,Prahlad Ho +10 more
- 01 Oct 2021
TL;DR: In this paper, the role of global coagulation assays in predicting long-term patient outcomes was investigated in patients with diabetes mellitus, and the results showed that patients with T2DM were more hypercoagulable than those with T1DM on most biomarkers.