26 Papers
31 Citations
Ge Jin is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Cancer & Innate immune system. The author has an hindex of 12, co-authored 21 publications. Previous affiliations of Ge Jin include University Hospitals of Cleveland.
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Papers
Human antimicrobial peptides and cancer.
Ge Jin,Aaron Weinberg +1 more
TL;DR: A new paradigm in cancer biology as it relates to AMP activity in neoplasia is introduced to address the following questions: Is there evidence that AMPs contribute to tumor promoting microenvironments?
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Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA
Lechuang Chen,Zhimin Feng,Hong Yue,Hong Yue,Douglas A. Bazdar,Uri Mbonye,Chad A. Zender,Clifford V. Harding,Leslie A Bruggeman,Jonathan Karn,Jonathan Karn,Scott F. Sieg,Scott F. Sieg,Bingcheng Wang,Ge Jin,Ge Jin +15 more
TL;DR: It is shown that exosomes released from HIV-infected T cells and those purified from blood of HIV-positive patients stimulate proliferation, migration and invasion of oral/oropharyngeal and lung cancer cells.
Overexpression of human β-defensin-3 in oral dysplasia: Potential role in macrophage trafficking
Hameem I. Kawsar,Aaron Weinberg,Stanley A. Hirsch,Andrea Venizelos,Scott Howell,Bin Jiang,Ge Jin +6 more
TL;DR: The results suggest that hBD-3 serves as a mitogen responsive gene in the initiation of oral cancer and may act as a motility signal to recruit tumor-associated macrophages.
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Sh3pxd2b Mice Are a Model for Craniofacial Dysmorphology and Otitis Media
Bin Yang,Cong Tian,Zhi guang Zhang,Feng chan Han,Rami Azem,Heping Yu,Ye Zheng,Ge Jin,James E. Arnold,Qing Yin Zheng +9 more
TL;DR: It was found that all mice that had the Sh3pxd2bnee mutation went on to develop craniofacial dysmorphologies and subsequently otitis media, by as early as 11 days of age, and all mutants were found to have hearing impairment.
Assessment of the incidence of squamous cell papilloma of the esophagus and the presence of high-risk human papilloma virus.
TL;DR: The incidence of esophageal papilloma has increased by fourfolds over the past 14 years, and about half of the tested patients demonstrated high risk HPV, which may suggest a potential growing risk for esphageal squamous cell cancer in the future.
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