Gaurav Gupta
Johns Hopkins University
42 Papers
110 Citations
Gaurav Gupta is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 11, co-authored 16 publications. Previous affiliations of Gaurav Gupta include Stanford University.
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Papers
Instrumentation of the osteoporotic spine: biomechanical and clinical considerations
TL;DR: Novel surgical approaches and instruments have been designed to decrease construct failures in this patient population by reducing implant pullout, subsidence, and incidence of revision surgery.
185
Impaired shear stress-induced nitric oxide production through decreased NOS phosphorylation contributes to age-related vascular stiffness
Kevin G. Soucy,Sungwoo Ryoo,Alexandre M. Benjo,Hyun Kyo Lim,Hyun Kyo Lim,Gaurav Gupta,Jayson S. Sohi,Jeremy Elser,Miguel A. Aon,Daniel Nyhan,Artin A. Shoukas,Dan E. Berkowitz +11 more
TL;DR: In this article, the effects of aging on shear stress-inducible arteries were investigated, showing that increased arterial stiffness and endothelial dysfunction contribute to multiple vascular diseases and are hallmarks of cardiovascular aging.
150
Apurinic/Apyrmidinic Endonuclease 1 Regulates Endothelial NO Production and Vascular Tone
Byeong Hwa Jeon,Gaurav Gupta,Young Chul Park,Young Chul Park,Bing Qi,Azeb Haile,Firdous A. Khanday,Yan Xia Liu,Jin Man Kim,Michitaka Ozaki,Anthony R. White,Dan E. Berkowitz,Kaikobad Irani +12 more
TL;DR: Findings uncover a novel physiological role for APE1/ref-1 in regulating vascular tone by governance of eNOS activity and bioavailable NO.
94
Molecular diagnosis of ABMR with or without donor‐specific antibody in kidney transplant biopsies: Differences in timing and intensity but similar mechanisms and outcomes
Philip F. Halloran,Katelynn S. Madill-Thomsen,S. Pon,Majid L N Sikosana,Georg A. Böhmig,C. Bromberg,Gunilla Einecke,Farsad Eskandary,Gaurav Gupta,Luis G. Hidalgo,M. Myslak,Ondrej Viklicky,Agnieszka Perkowska-Ptasińska +12 more
TL;DR: DSA‐negative mABMR is on average earlier, less active, and more often C4d‐negative but has similar graft loss, and genome‐wide analysis suggests that it involves the same mechanisms.
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Alagebrium in combination with exercise ameliorates age-associated ventricular and vascular stiffness
Jochen Steppan,Huang Tran,Alexandre M. Benjo,Laxsmi Pellakuru,Viachaslau Barodka,Sungwoo Ryoo,Sineád M. Nyhan,Craig Lussman,Gaurav Gupta,Anthony R. White,João Paulo Lima Daher,Artin A. Shoukas,Benjamin D. Levine,Dan E. Berkowitz +13 more
TL;DR: The results suggest that prevention of the formation of new AGEs (with exercise) and breakdown of already formed A GEs ( with ALT) may represent a therapeutic strategy for age-related ventricular and vascular stiffness.
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