Gary S. Linn
Nathan Kline Institute for Psychiatric Research
22 Papers
260 Citations
Gary S. Linn is an academic researcher from Nathan Kline Institute for Psychiatric Research. The author has contributed to research in topics: Phencyclidine & Fluphenazine. The author has an hindex of 11, co-authored 19 publications. Previous affiliations of Gary S. Linn include New York University.
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Papers
Spatiotemporal structure of intracranial electric fields induced by transcranial electric stimulation in humans and nonhuman primates.
Alexander Opitz,Alexander Opitz,Arnaud Falchier,Chao-Gan Yan,Chao-Gan Yan,Erin M. Yeagle,Gary S. Linn,Pierre Mégevand,Axel Thielscher,Axel Thielscher,Axel Thielscher,Ross A. Deborah,Michael P. Milham,Michael P. Milham,Ashesh D. Mehta,Charles E. Schroeder,Charles E. Schroeder +16 more
TL;DR: This study directly measure the spatial and temporal characteristics of the electric field generated by TES using stereotactic EEG (s-EEG) electrode arrays implanted in cebus monkeys and surgical epilepsy patients to provide crucial information of the underlying biophysics in TES applications in humans and the optimization and design of TES stimulation protocols.
Reversal of phencyclidine-induced prepulse inhibition deficits by clozapine in monkeys
TL;DR: Clozapine was distinguishable from haloperidol by its ability to attenuate PCP-induced deficits in PPI, and the results provide further evidence that PPI in nonhuman primates may provide an important animal model for the development of novel anti-schizophrenia medications.
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Electric field dynamics in the brain during multi-electrode transcranial electric stimulation.
Ivan Alekseichuk,Arnaud Falchier,Gary S. Linn,Ting Xu,Michael P. Milham,Michael P. Milham,Charles E. Schroeder,Charles E. Schroeder,Alexander Opitz +8 more
TL;DR: Direct invasive recordings from two non-human primates during multi-electrode TACS are used to characterize electric field magnitude and phase as a function of the phase of stimulation currents and report a novel “traveling wave” stimulation where the location of the electric field maximum changes over the stimulation cycle.
Limitations of ex vivo measurements for in vivo neuroscience
Alexander Opitz,Arnaud Falchier,Gary S. Linn,Michael P. Milham,Michael P. Milham,Charles E. Schroeder,Charles E. Schroeder +6 more
TL;DR: It is shown that pre- vs. postmortem, TES-induced intracranial electric fields differ significantly in both strength and frequency response dynamics, even while controlling for confounding factors such as body temperature.
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Phencyclidine (PCP)-induced deficits of prepulse inhibition in monkeys.
Gary S. Linn,Daniel C. Javitt +1 more
TL;DR: The ability of PCP to induce schizophrenia-like deficits in PPI suggests that PPI in nonhuman primates may provide an important animal model for the development of novel anti-schizophrenia medications.
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