Gary D. Buffinton
Australian National University
7 Papers
66 Citations
Gary D. Buffinton is an academic researcher from Australian National University. The author has contributed to research in topics: Plasmodium vinckei & Lipid peroxidation. The author has an hindex of 7, co-authored 7 publications.
Chat about Author
Papers
Depleted mucosal antioxidant defences in inflammatory bowel disease
Gary D. Buffinton,William F. Doe +1 more
TL;DR: These observations support the earlier findings of decreased reduced and total ascorbic acid in inflamed IBD mucosa and demonstrate that the loss of chemical antioxidant defences affects almost all the major components.
257
Detection of short-chain carbonyl products of lipid peroxidation from malaria-parasite (Plasmodium vinckei)-infected red blood cells exposed to oxidative stress.
TL;DR: It is demonstrated that products of lipid peroxidation other than malonaldehyde are formed during the exposure of malaria-infected RBCs in vitro to drugs that generate reactive oxygen species and have anti-parasitic activity.
Toxicity of certain products of lipid peroxidation to the human malaria parasite Plasmodium falciparum.
TL;DR: The aldehydes found to be inhibitory against P. falciparum could contribute to both the non-antibody host responses against this parasite and the antimalarial effects of radical-generating compounds such as t-butyl hydroperoxide, hydrogen peroxide, alloxan, isouramil, divicine and primaquine.
33
Bleomycin-detectable iron in plasma from Plasmodium vinckei vinckei-infecied mice
TL;DR: It is speculated that this iron could catalyse reduction of peroxides in vivo and thus play a role in malaria pathology.
12
Activation of cyclic AMP-dependent protein kinase in macrophages.
TL;DR: It is proposed that the activation of cyclic AMP-PK plays a central role in the response of macrophages to both endogenously-generated and exogenously added PGE.
9