Gang Pei
Chinese Academy of Sciences
12 Papers
58 Citations
Gang Pei is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Catalysis & Pyrrolidine. The author has an hindex of 3, co-authored 11 publications.
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Papers
Biomarkers of aging
Hà Dương Xuân Bảo,Jiani Cao,Mengting Chen,Min Chen,Wei Chen,Xiao Chen,Yanhao Chen,Yu Chen,Yutian Chen,Zhiyang Chen,Jagadish K. Chhetri,Yingjie Ding,Junlin Feng,Jun Guo,Mengmeng Guo,Chuting He,Yujuan Jia,Haiping Jiang,Ying Jing,Dingfeng Li,Jiaming Li,Jingyi Li,Qinhao Liang,Rui Liang,Xiaoqian Liu,Zuojun Liu,Oscar Junhong Luo,Jianwei Lv,Jingyi Ma,Jiawei Nie,Xinhua Qiao,Xinpei Sun,Xiaoqiang Tang,Jianfang Wang,Qiaoran Wang,Siyuan Wang,Xuan Wang,Yaning Wang,Yuhan Wang,Kai Xia,Fuhui Liao,Lingyan Xu,Yingying Xu,Haoteng Yan,Liang Yang,Ruici Yang,Yuanxin Yang,Yilin Ying,Le Zhang,Weiwei Zhang,Wenwan Zhang,Xuning Zhang,Zhuo Zhang,Min Zhou,Rui Zhou,Qingchen Zhu,Zhengmao Zhu,Feng Cao,Zhongwei Cao,P. Chang,Chang Chen,Guobing Chen,Hou-Zao Chen,Jun Chen,Weimin Ci,Bi-Sen Ding,Qiurong Ding,Feng Gao,J.H. Han,Kai Huang,Zhenyu Ju,Qing-Peng Kong,Ji Li,Jian Li,Xin Li,Baohua Liu,Feng Liu,Lin Liu,Qiang Liu,Qiang Liu,Xingguo Liu,Yong Liu,Xianghang Luo,Shuai Ma,Xinran Ma,Zhiyong Mao,Jing Nie,Yaojin Peng,Jing Qu,Jie Ren,Ruibao Ren,Moshi Song,Zhou Songyang,Yi E. Sun,Mei Tian,Sheng Wang,Si Qi Wang,Xia Wang,Xiaoning Wang,Yan-Jiang Wang,Yunfang Wang,Catherine C L Wong,Andy Peng Xiang,Yichuan Xiao,Zhengwei Xie,Daichao Xu,Jing Ye,Rui Yue,Cuntai Zhang,Hongbo Zhang,Liang Zhang,Weiqi Zhang,Yong Zhang,Yun-wu Zhang,Zhuohua Zhang,Tongbiao Zhao,Yuzheng Zhao,Dahai Zhu,Weiguo Zou,Gang Pei,Guang-Hui Liu +120 more
TL;DR: Aging biomarkers are a combination of biological parameters to assess agerelated changes, track the physiological aging process, and predict the transition into a pathological status as discussed by the authors , which can help us answer the following three fundamental questions in aging research: How old are we? Why do we get old? And how can we age slower?
Synthesis and Biological Evaluation of 1,3,3,4‐Tetrasubstituted Pyrrolidine CCR5 Receptor Antagonists. Discovery of a Potent and Orally Bioavailable Anti‐HIV Agent
Dawei Ma,Shanghai Yu,Ben Li,Li Chen,Renhai Chen,Kunqian Yu,Linqi Zhang,Linqi Zhang,Zhiwei Chen,Dafang Zhong,Zheng Gong,Renxiao Wang,Hualiang Jiang,Gang Pei +13 more
TL;DR: Results indicated that (3R,4S)‐configuration in the series of compounds is favored for their interaction with the CCR5 receptor, and compound 30 is a promising candidate for the treatment of HIV‐1 infection.
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Studies on the structure-activity relationship of 1,3,3,4-tetra-substituted pyrrolidine embodied CCR5 receptor antagonists. Part 2: Discovery of highly potent anti-HIV agents.
Ben Li,Eric Dale Jones,Enkun Zhou,Li Chen,Dean Baylis,Shanghai Yu,Miao Wang,Xing He,Jonathan Coates,David Ian Rhodes,Gang Pei,John Deadman,Xin Xie,Dawei Ma +13 more
TL;DR: Modification of 1,3, 3,4-tetra-substituted pyrrolidine embodied CCR5 receptor antagonists revealed that introducing a fluoro group at the 3-position of the3-phenyl group to reduce metabolism did not adversely affect the high potency against HIV infection, and replacing the piperidine ring with a tropane ring could deliver the most potent anti-HIV agents.
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Studies on the structure-activity relationship of 1,3,3,4-tetra-substituted pyrrolidine embodied CCR5 receptor antagonists. Part 1: Tuning the N-substituents.
Li Ben,Eric Dale Jones,Enkun Zhou,Chen Li,Dean Baylis,Shanghai Yu,Miao Wang,Xing He,Jonathan Coates,David Ian Rhodes,Gang Pei,John Deadman,Xin Xie,Dawei Ma +13 more
TL;DR: A novel series of CCR5 antagonists has been identified, utilizing the lead, nifeviroc, which were further modified based on bioisosteric principles, resulting in potent analogues with low toxic properties.
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Elaboration of the OxazepineRing System via CuI/l-Proline-Catalyzed IntramolecularAryl Amination
TL;DR: In this article, a two-step approach for assembling oxazepines is described, which started from 2-aminophenols and substituted 2-bromobenzyl bromides and used CuI/L-proline-catalyzed coupling reaction as the key step.
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