Gang Pan
Shanghai University
9 Papers
12 Citations
Gang Pan is an academic researcher from Shanghai University. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 3, co-authored 4 publications.
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Papers
Mitochondrial translocation of cofilin-1 promotes apoptosis of gastric cancer BGC-823 cells induced by ursolic acid.
Qing-Feng Tang,Qing Ji,Yu Tang,Teng Chen,Gang Pan,Song-Jiao Hu,Yi-Jie Bao,Wen Peng,Peihao Yin +8 more
TL;DR: It is found in apoptotic gastric cancer BGC-823 cells induced by ursolic acid that a translocation of cofilin-1 protein from the cytoplasm to the mitochondria promoted the release of cytochrome c from the mitochondrial to the cy toplasm, thereby activating the caspase cascade and finally inducing gastric cancers cell apoptosis.
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Microalgae-derived carbon quantum dots mediated formation of metal sulfide nano-adsorbents with exceptional cadmium removal performance.
Chen Wang,Lei Bi,Jingzhang Liu,Bang Huang,Fengbang Wang,Yichang Zhang,Chongchao Yao,Gang Pan,Maoyong Song +8 more
TL;DR: In this article , microalgae-derived carbon quantum dots (CQDs) were used as a green modifier for mediating nano-MnS/FeS formation to enhance Cd2+ removal.
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Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer
Gang Pan,Yi-Jie Bao,Jie Xu,Tao Liu,Cheng Liu,Yanyan Qiu,Shi Xiaojing,Hui Yu,Ting-ting Jia,Xia Yuan,Zeting Yuan,Peihao Yin,Yi-jun Cao +12 more
TL;DR: It was demonstrated that the tumor-targeting polymeric prodrug showed improved anticancer performance both in vitro and in vivo in comparison with that of free BUF.
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Development of (G3-C12)-mediated camptothecin polymeric prodrug targeting to Galectin-3 receptor against androgen-independent prostate cancer.
TL;DR: Compared to free CPT, the multifunctional polymeric prodrug demonstrated improved water solubility and stability, higher intracellular uptake, and enhanced cytotoxicity in DU145 cells in vitro and in vivo and could be a promising drug in the treatment of androgen-independent prostate cancer.
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Synthesis and biological evaluation of novel aromatic amide derivatives as potential BCR-ABL inhibitors.
Xiu-jun Wang,Zhou Xu,Jing Feng,Gang Pan,Xingbei He,Mingxiao Lv,Hui-Na Chen,Wentao Jiang,Jing Ji,Mingli Yang +9 more
TL;DR: In this article , a series of aromatic amide derivatives based on several generations of BCR-ABL1 kinase inhibitors were designed and synthesized, and compared with Imatinib, these compounds showed significant proliferation inhibitory activities of HL-60 and K562 in cell activity assay.
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