Gang Chen
Xi'an Shiyou University
8 Papers
130 Citations
Gang Chen is an academic researcher from Xi'an Shiyou University. The author has contributed to research in topics: Isatin & Oxindole. The author has an hindex of 6, co-authored 8 publications. Previous affiliations of Gang Chen include Chinese Academy of Sciences.
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Papers
L-proline-catalyzed asymmetric aldol condensation of N-substituted isatins with acetone
TL;DR: In this article, an L-proline-catalyzed asymmetric aldol condensation of several isatin derivatives with acetone is reported, and the desired products were obtained in highly yield with the ee among 30-79%.
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Spiro[pyrrolidine-2,3'-oxindole] derivatives synthesized by novel regionselective 1,3-dipolar cycloadditions.
Gang Chen,Gang Chen,Jing Yang,Suo Gao,Hongping He,Shun-Lin Li,Ying-Tong Di,Ying Chang,Yang Lu,Xiao-Jiang Hao +9 more
TL;DR: A series of spiro-oxindole derivatives was synthesized by novel regioselective 1,3-dipolar cycloadditions of isatin, α-amino acids, and (E)-β-aryl-nitro-olefins, and the major products showed different regiOSElectivity compared to previously reported spiro.
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Synthesis and Bioactivity Evaluation of 3-Hydroxy-3-(phenylethynyl)indol-2-one Analogues
Gang Chen,Gang Chen,Ye Wang,Suo Gao,Hong-Ping He,Shun-Lin Li,Jian-Xin Zhang,Jian Ding,Xiao-Jiang Hao +8 more
TL;DR: A series of propargylic alcohol was synthesized by the addition of phenylacetylene to isatin and its N-substituted derivatives for the first time as discussed by the authors.
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Theoretical study of the regioselectivity of the Huisgen reaction
TL;DR: In this article, the possible mechanism of the Huisgen reaction of oxindole azomethine ylide and the substituent of olefins was investigated using a B3LYP/6-311G* level of theory, and the results show that the regioselection depends on the energy barrier between the stacking state and the regioisomer.
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Rapid synthesis and bioactivities of 3-(nitromethylene)indolin-2-one analogues
Gang Chen,Gang Chen,Xiao-Jiang Hao,Qian-Yun Sun,Jian Ding +4 more
- 01 Oct 2010
TL;DR: 3-(Nitromethylene)indolin-2-one analogues are valued protective agents against H2O2-induced apoptosis using PC12 cells, and for their cytotoxicity against the A549 and P388 lung cancer cell lines.
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