Das lokal inoperable prasakrale Rezidiv beim Rektumkarzinom stellt onkologisch eine besondere Schwierigkeit dar, da in der Regel bei der Diagnosestellung bereits Inoperabilitat vorliegt, die palliative Radiatio nur zeitlich begrenzt wirksam ist und die systemische Chemotherapie bisher nicht den Nachweis wirksamer Palliation oder gar der Lebenszeitverlangerung erbringen konnte.

Intraarterielle Chemotherapie beim inoperablen Rektumkarzinom und Rektumkarzinomrezidiv

PURPOSE Evaluation of intraarterial cancer treatment in recurrent pelvic tumors, which were resistent to other treatment modalities. PATIENTS AND METHODS Ninety-seven patients suffering from pelvic recurrences originating from bladder (n = 40), rectum (n = 19), cervix (n = 21) oder other organs (n = 17) were treated by intraarterial chemotherapy (111 times) or transcatheter embolisation (52 times). RESULTS Less than 20% of our patients had remission of the tumor burden but tumor symptoms (especially pain and bleeding) could be controlled in 35 to 87% of the patients. The main complication was a muscle necrosis after intraarterial chemotherapy because of recurrent bladder cancer. CONCLUSION Intraarterial cancertherapy is a useful procedure for symptomatic treatment of tumor symptoms especially in case of bleeding. Local tumor control can only be achived in a minority of the patients.

[Intra-arterial treatment of therapy-resistant residual tumors of the pelvis].

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[Intra-arterial treatment of therapy-resistant residual tumors of the pelvis].