G. Krumpl
University of Vienna
39 Papers
257 Citations
G. Krumpl is an academic researcher from University of Vienna. The author has contributed to research in topics: Blood pressure & Hemodynamics. The author has an hindex of 10, co-authored 38 publications.
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Papers
Bolus application of landiolol and esmolol: comparison of the pharmacokinetic and pharmacodynamic profiles in a healthy Caucasian group
TL;DR: Compared to esmolol, landiolol shows a more prominent and pronounced bradycardic effect in relation to its blood pressure-lowering effect, an action profile that might be of specific advantage in the perioperative setting.
31
Mode of QT correction for heart rate: implications for the detection of inhomogeneous repolarization after myocardial infarction.
TL;DR: In 22 conscious, chronically instrumented dogs, the adequacy of QT correction contributes significantly to the detection of inhomogeneous ventricular recovery after acute myocardial infarction.
28
Comparison of the haemodynamic effects of the selective bradycardic agent UL-FS 49, with those of propranolol during treadmill exercise in dogs.
TL;DR: Patients with moderate coronary insufficiency or patients with coronary vessel disease and mild left ventricular failure may attain a higher exercise limit under selective bradycardia with UL‐FS 49 in comparison to that possible with a β‐adrenoceptor antagonist, such as propranolol.
22
Can exercise-induced regional contractile dysfunction be prevented by selective bradycardic agents?
TL;DR: Propranolol (0.5 mg×kg−1×5 min−1), alinidine (1 mg×kg−1/5 min −1), and benzazepinon UL-FS 49 were investigated in a canine model of exercise-induced transient myocardial dysfunction, mimicking exerciseinduced functional impairment during angina pectoris in man as mentioned in this paper.
22
Landiolol in patients with septic shock resident in an intensive care unit (LANDI-SEP): study protocol for a randomized controlled trial.
Martin Unger,Andrea Morelli,Mervyn Singer,Peter Radermacher,Sebastian Rehberg,Helmut Trimmel,Michael Joannidis,Gottfried Heinz,Vladimir Cerny,Pavel Dostál,Christian Siebers,Fabio Guarracino,Francesca Pratesi,Gianni Biancofiore,Massimo Girardis,Pavla Kadlecová,Olivier Bouvet,Michael Zörer,Barbara Grohmann-Izay,Kurt Krejcy,Christoph Klade,G. Krumpl +21 more
TL;DR: This multicenter study is to demonstrate that administration of the highly beta1-selective and ultrashort-acting beta blocker landiolol in patients with septic shock and persistent tachycardia is effective in reducing and maintaining HR without increasing vasopressor requirements.