G. Jitender Dev
Indian Institute of Chemical Technology
7 Papers
17 Citations
G. Jitender Dev is an academic researcher from Indian Institute of Chemical Technology. The author has contributed to research in topics: Chemistry & Minimum bactericidal concentration. The author has an hindex of 5, co-authored 7 publications. Previous affiliations of G. Jitender Dev include Academy of Scientific and Innovative Research.
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Papers
Synthesis of novel triazole/isoxazole functionalized 7-(trifluoromethyl)pyrido[2,3-d]pyrimidine derivatives as promising anticancer and antibacterial agents.
R. Naresh Kumar,R. Naresh Kumar,G. Jitender Dev,G. Jitender Dev,N. Ravikumar,D. Krishna Swaroop,D. Krishna Swaroop,B. Debanjan,G. Bharath,Banda Narsaiah,Banda Narsaiah,S. Nishant Jain,A. Gangagni Rao +12 more
TL;DR: A series of novel 1,2,3-triazole/isoxazole functionalized pyrido-pyrimidine derivatives 6a-c, 7a-h and 8a-e showed highest activity against PANC-1 (pancreatic cancer) and A549 (lung cancer) cell lines respectively and more than standard.
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Synthesis of novel 1,2,3-triazole/isoxazole functionalized 2H-Chromene derivatives and their cytotoxic activity.
K. Ratnakar Reddy,P. Sambasiva Rao,G. Jitender Dev,Yedla Poornachandra,C. Ganesh Kumar,P. Shanthan Rao,Banda Narsaiah +6 more
TL;DR: A series of novel 2-(1,2,3-triazolylmethoxy) 5a-q and isoxazole tagged 6a-g 2H-Chromene derivatives and among all the compounds, 5f, 5g, 5l, 5q showed promising activity at <20 μM concentration.
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Studies on synthesis of novel pyrido[2,3-d]pyrimidine derivatives, evaluation of their antimicrobial activity and molecular docking
B. Veeraswamy,Devarapaga Madhu,Devarapaga Madhu,G. Jitender Dev,G. Jitender Dev,Yedla Poornachandra,Yedla Poornachandra,G. Shravan Kumar,C. Ganesh Kumar,C. Ganesh Kumar,Banda Narsaiah,Banda Narsaiah +11 more
TL;DR: The results reveal that the compound pyrido[2,3-d]pyrimidine derivative 6e altered the sterol profile which may exert its antifungal activity through inhibition of ergosterol biosynthesis and could be an ideal candidate for antIFungal therapy.
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Synthesis of novel ethyl 2,4-disubstituted 8-(trifluoromethyl)pyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidine-9-carboxylate derivatives as promising anticancer agents.
N. Ravi Kumar,Yedla Poornachandra,D. Krishna Swaroop,G. Jitender Dev,C. Ganesh Kumar,Banda Narsaiah +5 more
TL;DR: Compounds 8a, 9f and 9k which showed promising anticancer activity have been identified and were able to inhibit the human topoisomerase I (TopI) activity similar to that of camptothecin.
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Synthesis of novel amide functionalized 2H-chromene derivatives by Ritter amidation of primary alcohol using HBF4·OEt2 as a mild and versatile reagent and evaluation of their antimicrobial and anti-biofilm activities.
K. Ratnakar Reddy,Yedla Poornachandra,G. Jitender Dev,G. Mallareddy,Jagadeesh Babu Nanubolu,C. Ganesh Kumar,Banda Narsaiah +6 more
TL;DR: The structure verses activity relationship of compound 3g revealed that the presence of two bromine atoms at sixth and R position promotes high activity, and was more potent for antimicrobial, MBC and anti bio-film activities.
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