G.E. Foley
Karolinska Institutet
14 Papers
295 Citations
G.E. Foley is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: RNA & Cell nucleus. The author has an hindex of 11, co-authored 14 publications. Previous affiliations of G.E. Foley include Boston Children's Hospital & National Foundation for Cancer Research.
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Papers
Chemical differentiation with fluorescent alkylating agents in Vicia faba metaphase chromosomes.
Torbjörn Caspersson,Torbjörn Caspersson,Lore Zech,Lore Zech,E.J. Modest,E.J. Modest,G.E. Foley,G.E. Foley,U. Wagh,U. Wagh,E. Simonsson,E. Simonsson +11 more
TL;DR: A bifunctional highly fluorescent quinacrine mustard was shown to give chromosome breaks preferentially localized to heterochromatic chromosome regions (identifiable by cold treatment) in the M-chromosome.
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DNA-binding fluorochromes for the study of the organization of the metaphase nucleus
Torbjörn Caspersson,Torbjörn Caspersson,Lore Zech,Lore Zech,E.J. Modest,E.J. Modest,G.E. Foley,G.E. Foley,U. Wagh,U. Wagh,E. Simonsson,E. Simonsson +11 more
TL;DR: Great and reproducible differences in the uptake of the fluorescent reagents by different chromosome regions were observed and a good correlation was found between regions reacting with several different fluorescent compounds and heterochromatin as defined by cold treatment.
277
Cytochemical observations on the nucleolus-ribosome system: Effects of actinomycin D and nitrogen mustard☆
Torbjörn Caspersson,Torbjörn Caspersson,Torbjörn Caspersson,S. Farber,S. Farber,S. Farber,G.E. Foley,G.E. Foley,G.E. Foley,D. Killander,D. Killander,D. Killander +11 more
TL;DR: Cytochemical analyses of cell populations exposed to actinomycin D and nitrogen mustard support the concept that the nucleolus-associated chromatin is concerned primarily with the synthesis of ribosomal RNA—either directly, or by the mediation of a “messenger” fraction of RNA.
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Cytochemical differences between mammalian cell lines of normal and neoplastic origins. correlation with heterotransplant- ability in syrian hamsters.
Torbjörn Caspersson,Torbjörn Caspersson,Torbjörn Caspersson,G.E. Foley,G.E. Foley,G.E. Foley,D. Killander,D. Killander,D. Killander,G. Lomakka,G. Lomakka,G. Lomakka +11 more
TL;DR: It is of interest that certain cytochemical attributes of populations of neoplastic cells in vivo are retained by such populations when isolated and maintained in vitro, and that these cyt biochemical attributes correlate with the heterotransplantability of such cell lines to the cheek pouch of the Syrian hamster.
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Cytochemical evaluation of metabolic inhibitors in cell culture.
Torbjörn Caspersson,Torbjörn Caspersson,S. Farber,S. Farber,G.E. Foley,G.E. Foley,D. Killander,D. Killander,Anders Zetterberg,Anders Zetterberg +9 more
TL;DR: This method permits the in situ determination of the amount of DNA, RNA, and protein in individual cells in populations of heterogeneous cells, and the effects of inhibitory agents on these biosynthetic processes.
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