G. Chris Fillmore
University of Utah
8 Papers
52 Citations
G. Chris Fillmore is an academic researcher from University of Utah. The author has contributed to research in topics: Lymphoma & Gene expression. The author has an hindex of 7, co-authored 8 publications. Previous affiliations of G. Chris Fillmore include ARUP Laboratories & University of Michigan.
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Papers
Minimizing the time required for DNA amplification by efficient heat transfer to small samples
TL;DR: A rapid temperature cycler of low thermal mass was constructed and a 536-bp beta-globin fragment of human genomic DNA was easily visualized with ethidium bromide on agarose gels with rapid cycling.
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The proteomic signature of NPM/ALK reveals deregulation of multiple cellular pathways
Megan S. Lim,M. Carlson,David K. Crockett,G. Chris Fillmore,David R. Abbott,Olaotan F. Elenitoba-Johnson,Sheryl R. Tripp,George Z. Rassidakis,L. Jeffrey Medeiros,Philippe Szankasi,Kojo S.J. Elenitoba-Johnson +10 more
TL;DR: Diverse NPM/ALK-induced changes affecting cell proliferation, ribosome synthesis, survival, apoptosis evasion, angiogenesis, and cytoarchitectural organization are identified and revealed.
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Expression of Akt (protein kinase B) and its isoforms in malignant lymphomas.
G. Chris Fillmore,Qifu Wang,Michael J. Carey,Chan-Hwan Kim,Kojo S.J. Elenitoba-Johnson,Megan S. Lim +5 more
TL;DR: The results suggest that there is constitutive activation of Akt in the majority of primary human lymphomas and hematopoietic cell lines and support its proposed key role in lymphoma cell survival.
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Microarray analysis of B-cell lymphoma cell lines with the t(14;18).
Ryan S. Robetorye,Sandra D. Bohling,John Morgan,G. Chris Fillmore,Megan S. Lim,Megan S. Lim,Kojo S.J. Elenitoba-Johnson,Kojo S.J. Elenitoba-Johnson +7 more
TL;DR: The utility of cDNA microarray analysis is demonstrated for the assessment of global transcriptional changes that characterize t(14;18)-positive cell lines, and also for the identification of novel genes that could potentially contribute to the genesis and progression of non-Hodgkin's lymphomas with this translocation.
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Analysis of phosphatase and tensin homolog tumor suppressor interacting proteins by in vitro and in silico proteomics
David K. Crockett,G. Chris Fillmore,Kojo S.J. Elenitoba-Johnson,Kojo S.J. Elenitoba-Johnson,Megan S. Lim,Megan S. Lim +5 more
TL;DR: The goal of this study was to characterize the PTEN interactome using affinity pull‐down and tandem mass spectrometry (MS/MS) and validated a subset of the proteins present in the PTen interactome by performing immunoprecipitation using an anti‐PTEN antibody and establishing the presence of theprotein in the immunocomplex by Western blot analysis.
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