Fumio Takeuchi
Aichi Medical University
14 Papers
136 Citations
Fumio Takeuchi is an academic researcher from Aichi Medical University. The author has contributed to research in topics: Vitamin & Pyridoxal phosphate. The author has an hindex of 8, co-authored 14 publications.
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Papers
Rosmarinic acid inhibits the formation of reactive oxygen and nitrogen species in RAW264.7 macrophages
Shanlou Qiao,Weihua Li,Ryoko Tsubouchi,Miyako Haneda,Keiko Murakami,Fumio Takeuchi,Yukio Nisimoto,Masataka Yoshino +7 more
TL;DR: Ros A can act as an effective protector against peroxynitrite-mediated damage, and as a potent inhibitor of superoxide and NO synthesis; the inhibition of the formation of reactive oxygen and nitrogen species are partly based on its ability to inhibit the serine phosphorylation of Iκ-Bα.
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Purification and properties of kynureninase from rat liver.
TL;DR: Kynureninase [L-kynurenine hydrolase EC 3.3] has been purified 614-fold from rat liver cytosol and was found to be homogeneous by the criteria of disc gel electrophoresis and sucrose gradient centrifugation.
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Purification, characterization and identification of rat liver mitochondrial kynurenine aminotransferase with α-aminiadipate aminotransferase
TL;DR: Observations indicate that kynurenine aminotransferase is identical with α-aminoadipate aminotsferase, which is strongly inhibited by Hg 2+ and p -chloromercuribenzoate.
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Kynurenine metabolism and xanthurenic acid formation in vitamin B6-deficient rat after tryptophan injection
TL;DR: Observations indicated that the production of xanthurenic acid after tryptophan injection was favorable in B6-deficient kidney with respect to enzyme activities and substrate concentrations, and suggested that kidney took up kynurenine or 3-hydroxykynurenines from blood and after conversion of them it excreted xanthurnic or kynurenic Acid into urine.
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Glutathione Levels and Related Enzyme Activities in Vitamin B-6-Deficient Rats Fed a High Methionine and Low Cystine Diet
TL;DR: It is indicated that although the activities of enzymes that synthesize cysteine from methionine were decreased by vitamin B-6 deficiency, the level of synthesis and supply of cystine in vitamin B -6-deficient rats were sufficient to maintain the same glutathione level as in controls, and that glutathionine utilization in the liver was accelerated by Vitamin B- 6 deficiency.
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