Fujun Sun
Tianjin Medical University
9 Papers
Fujun Sun is an academic researcher from Tianjin Medical University. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 1, co-authored 1 publications.
Chat about Author
Papers
Hepatitis C virus nonstructural protein 5A perturbs lipid metabolism by modulating AMPK/SREBP-1c signaling.
TL;DR: It is shown that the serum levels of ALT, FFAs and TG, as well as the accumulation of hepatic lipid droplets, were increased significantly in mice infected with NS5A-expressing lentiviral particles, and pharmacological activation or ectopic expression of AMPK neutralized the upregulation of SREBP-1c, ACC1 and FASN, and ameliorated hepatic cholesterol accumulation induced by NS5a.
Comparative genomic analyses reveal the genetic basis of the yellow-seed trait in Brassica napus
Cunmin Qu,Meichen Zhu,Ran Hu,Yongchao Niu,Si Chen,Huiyan Zhao,Chengxiang Li,Zhen Wang,Nengwen Yin,Fujun Sun,Zhiyou Chen,Shulin Shen,Guoxia Shang,Yan Zhou,Xingying Yan,Lijuan Wei,Liezhao Liu,Bin Yi,Jinmin Lian,Jiang Chuan Li,Zhanglin Tang,Ying Liang,Xinfu Xu,Rui Wang,Jiaming Yin,Huafang Wan,Hai Du,Wei Qian,Yourong Chai,Qingyuan Zhou,Yajun He,Silin Zhong,Xiao Qiu,Hao Yu,Hon-Ming Lam,Kun Lu,Fuyou Fu,Jiana Li +37 more
TL;DR: Combining in-depth fine mapping of a quantitative trait locus for seed color with other omics data reveal BnA09MYB47a, encoding an R2R3-MYB-type transcription factor, as the causal gene of a major QTL controlling the yellow-seed trait.
14
Genome-Wide Association Study of Glucosinolate Metabolites (mGWAS) in Brassica napus L.
Yunshan Tang,Guorui Zhang,Xinyue Jiang,Shulin Shen,Mingwei Guan,Yuhan Tang,Fujun Sun,Ran Hu,Si Chen,Huiyan Zhao,Jiana Li,Kun Lu,Nengwen Yin,Cunmin Qu +13 more
TL;DR: In this article , a genome-wide association study of six glucosinolate metabolites (mGWAS) in rapeseed was conducted, including three aliphatic glucosinsolates (m145 gluconapin, m150 glucobrassicanapin and m151 progoitrin), one aromatic glucossinolate (m157gluconasturtiin) and two indole glucosINolates, respectively.
TET1 mutations as a predictive biomarker for immune checkpoint inhibitors in colon adenocarcinoma
TL;DR: The ten-eleven translocation 1 (TET1), which is essential for active DNA demethylation, plays a multifaceted role in the pathogenesis of colorectal cancer as discussed by the authors .