Fujun Qin
University of Virginia
46 Papers
168 Citations
Fujun Qin is an academic researcher from University of Virginia. The author has contributed to research in topics: Gene & Biology. The author has an hindex of 17, co-authored 34 publications. Previous affiliations of Fujun Qin include Huazhong Agricultural University & Yale University.
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Papers
Down-regulation of a SILENT INFORMATION REGULATOR2-related histone deacetylase gene, OsSRT1, induces DNA fragmentation and cell death in rice.
TL;DR: The role of OsSRT1, one of the two SIR2-related genes found in rice (Oryza sativa), was investigated in this article, where RNA interference induced an increase of histone H3K9 (lysine-9 of H3) acetylation, leading to H2O2 production, DNA fragmentation, cell death, and lesions mimicking plant hypersensitive responses during incompatible interactions with pathogens.
203
Recurrent chimeric fusion RNAs in non-cancer tissues and cells
Mihaela Babiceanu,Fujun Qin,Zhongqiu Xie,Yuemeng Jia,Kevin Lopez,Nick Janus,Loryn Facemire,Shailesh Kumar,Yuwei Pang,Yanjun Qi,Iulia M. Lazar,Hui Li +11 more
TL;DR: Performing functional analyses on a few widely expressed fusions found that silencing them resulted in dramatic reduction in normal cell growth and/or motility, and explored the implications of these non-pathological fusions in cancer and in evolution.
Identification of Circular RNAs and Their Targets in Leaves of Triticum aestivum L. under Dehydration Stress.
TL;DR: A possible connection between the regulations of circRNAs with the expressions of functional genes in wheat leaves associated with dehydration resistance is revealed.
Down-Regulation of a SILENT INFORMATION REGULATOR2-Related Histone Deacetylase Gene, OsSRT1, Induces DNA Fragmentation and Cell Death in Rice 1(C)(W)
Limin Huang,Qianwen Sun,Fujun Qin,Chen Li,Yu Zhao,Dao-Xiu Zhou +5 more
- 01 Jan 2007
TL;DR: The data together suggest that the rice SIR2-like gene is required for safeguard against genome instability and cell damage to ensure plant cell growth, but likely implicates different molecular mechanisms than yeast and animal homologs.
136
Linc00210 drives Wnt/β-catenin signaling activation and liver tumor progression through CTNNBIP1-dependent manner.
Xiaomin Fu,Xiaoyan Zhu,Fujun Qin,Yong Zhang,Jizhen Lin,Yuechao Ding,Zihe Yang,Yiman Shang,Li Wang,Qinxian Zhang,Quanli Gao +10 more
TL;DR: Of interest, linc00210, CTNNBIP1 and Wnt/β-catenin signaling targeting can efficiently inhibit tumor growth and progression, and liver TIC propagation.