Froma Oberman
Hebrew University of Jerusalem
17 Papers
241 Citations
Froma Oberman is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: RNA-binding protein & Messenger RNA. The author has an hindex of 10, co-authored 11 publications.
Chat about Author
Papers
RNA-binding protein conserved in both microtubule- and microfilament-based RNA localization
Leora Havin,Anna Git,Zichrini Elisha,Froma Oberman,Karina Yaniv,Sigal Pressman Schwartz,Nancy Standart,Joel K. Yisraeli +7 more
TL;DR: It is shown that Vg1 RBP-binding sites correlate with vegetal localization, and the existence of a general, evolutionarily conserved mechanism for mRNA targeting is suggested.
A 69-kDa RNA-binding protein from Xenopus oocytes recognizes a common motif in two vegetally localized maternal mRNAs.
TL;DR: Data indicate that vegetally localized mRNAs share a binding motif that helps them achieve their intracellular distribution through specific RNA-protein interactions.
96
Inhibition of transcription of herpes simplex virus immediate early genes in interferon-treated human cells.
Froma Oberman,Amos Panet +1 more
TL;DR: It is suggested that IFN blocked HSV-1 replication primarily at a very early stage, during the onset of alpha mRNA transcription, which indicated that the IFN-mediated inhibition of HSVs replication is at a stage beyond viral penetration into the cytoplasm.
82
Vg1 RBP intracellular distribution and evolutionarily conserved expression at multiple stages during development.
Qinghong Zhang,Karina Yaniv,Froma Oberman,Uta Wolke,Anna Git,Menachem Fromer,William L. Taylor,Dirk Meyer,Nancy Standart,Erez Raz,Joel K. Yisraeli +10 more
TL;DR: Although Vg1 RBP RNA is detected in all blastomeres of the early embryo, the expression pattern in the one day old zebrafish embryo is almost identical to that of the equivalent stage Xenopus embryo, indicating that the zygotic expression pattern is similar in frogs and fish.
63
A role for VICKZ proteins in the progression of colorectal carcinomas: regulating lamellipodia formation.
Gilad W. Vainer,E Vainer-Mosse,Alon J. Pikarsky,Shailesh M. Shenoy,Froma Oberman,A Yeffet,Robert H. Singer,Eli Pikarsky,Joel K. Yisraeli +8 more
TL;DR: It is proposed that VICKZ proteins play an important role in CRC metastasis by shuttling requisite RNAs to the lamellipodia of migrating cells, which helps to facilitate the dynamic cell surface morphology required for cell motility.