Frida Belinky
National Institutes of Health
27 Papers
64 Citations
Frida Belinky is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Gene & GeneCards. The author has an hindex of 15, co-authored 23 publications. Previous affiliations of Frida Belinky include Tel Aviv University & National Evolutionary Synthesis Center.
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Papers
SARS-CoV-2 infection and persistence in the human body and brain at autopsy
Sydney Stein,Sabrina Ramelli,Alison Grazioli,Joon-Yong Chung,Manmeet Singh,Claude Kwe Yinda,Clayton W. Winkler,Junfeng Sun,James Dickey,Kris Ylaya,Sung Hee Ko,Andrew Platt,Peter D. Burbelo,Martha Quezado,Stefania Pittaluga,M. Purcell,Vincent J. Munster,Frida Belinky,Marcos J Ramos-Benitez,Eli Boritz,Izabella A. Lach,Daniel Herr,Joseph Rabin,Kapil K. Saharia,Ronson J. Madathil,Ali Tabatabai,Shahabuddin Soherwardi,Michael T. McCurdy,Karin E. Peterson,Jeffrey I. Cohen,Emmie de Wit,Kevin M. Vannella,Stephen M. Hewitt,David E. Kleiner,Daniel S. Chertow +34 more
TL;DR: In this paper , the authors carried out complete autopsies on 44 patients who died with COVID-19, with extensive sampling of the central nervous system in 11 of these patients, to map and quantify the distribution, replication and cell-type specificity of SARS-CoV-2 across the human body, including the brain, from acute infection to more than seven months following symptom onset.
PathCards: multi-source consolidation of human biological pathways.
Frida Belinky,Noam Nativ,Gil Stelzer,Shahar Zimmerman,Tsippi Iny Stein,Marilyn Safran,Doron Lancet +6 more
TL;DR: A combination of hierarchical clustering and nearest neighbor graph representation is exercised, with judiciously selected cutoff values, thereby consolidating 3215 human pathways from 12 sources into a set of 1073 SuperPaths, showing a substantial enhancement of the Super pathologists’ capacity to infer gene-to-gene relationships when compared with individual pathway sources, separately or taken together.
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MalaCards: an integrated compendium for diseases and their annotation
Noa Rappaport,Noam Nativ,Gil Stelzer,Michal Twik,Yaron Guan-Golan,Tsippi Iny Stein,Iris Bahir,Frida Belinky,C. Paul Morrey,Marilyn Safran,Doron Lancet +10 more
TL;DR: This work introduces MalaCards, an integrated database of human maladies and their annotations, modeled on the architecture and strategy of the GeneCards database ofhuman genes, and suggests that this broadly disposed network has a power-law degree distribution, suggesting this might be an inherent property of such networks.
VarElect: the phenotype-based variation prioritizer of the GeneCards Suite.
Gil Stelzer,Inbar Plaschkes,Danit Oz-Levi,Anna Alkelai,Tsviya Olender,Shahar Zimmerman,Michal Twik,Frida Belinky,Simon Fishilevich,Ron Nudel,Yaron Guan-Golan,David Warshawsky,Dvir Dahary,Asher Kohn,Yaron Mazor,Sergey Kaplan,Tsippi Iny Stein,Hagit N. Baris,Hagit N. Baris,Noa Rappaport,Marilyn Safran,Doron Lancet +21 more
TL;DR: VarElect is described, a comprehensive phenotype-dependent variant/gene prioritizer based on the widely-used GeneCards, which helps rapidly identify causal mutations with extensive evidence, and is indispensable for emerging clinical projects that involve thousands of whole exome/genome NGS analyses.
In-silico human genomics with GeneCards
Gil Stelzer,Irina Dalah,Tsippi Iny Stein,Yigeal Satanower,Naomi Rosen,Noam Nativ,Danit Oz-Levi,Tsviya Olender,Frida Belinky,Iris Bahir,Hagit Krug,Paul Perco,Bernd Mayer,Eugene Kolker,Marilyn Safran,Doron Lancet +15 more
TL;DR: The evolution and architecture of this project is described, including examples of synergistic applications in diverse areas such as synthetic lethality in cancer, the annotation of genetic variations in disease, omics integration in a systems biology approach to kidney disease, and bioinformatics tools.
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