Fred Hacker
Brigham and Women's Hospital
47 Papers
306 Citations
Fred Hacker is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Radiosurgery & Medicine. The author has an hindex of 14, co-authored 46 publications. Previous affiliations of Fred Hacker include Dana Corporation & Rush University Medical Center.
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Papers
A clinical comparison of patient setup and intra-fraction motion using frame-based radiosurgery versus a frameless image-guided radiosurgery system for intracranial lesions.
TL;DR: The overall system accuracy is similar to that reported for invasive frame-based SRS, and the intra-fraction motion was larger with mask-immobilization, but remains within a range appropriate for stereotactic treatment.
167
Stereotactic irradiation of the postoperative resection cavity for brain metastasis: a frameless linear accelerator-based case series and review of the technique
Paul J. Kelly,Y Lin,Alvin Y.C. Yu,Brian M. Alexander,Fred Hacker,Karen J. Marcus,Stephanie E. Weiss +6 more
TL;DR: Frameless stereotactic irradiation of the resection cavity after surgery for a brain metastasis is a safe and accurate technique that offers durable local control and defers the use of WBRT in select patients.
82
Local control after fractionated stereotactic radiation therapy for brain metastases
Selvan Rajakesari,Nils D. Arvold,Rachel B. Jimenez,Laura W. Christianson,M.C. Horvath,Elizabeth B. Claus,Elizabeth B. Claus,Alexandra J. Golby,Mark D. Johnson,Ian F. Dunn,Eudocia Q. Lee,Nan Lin,Scott Friesen,E. Mannarino,M Wagar,Fred Hacker,Stephanie E. Weiss,Brian M. Alexander +17 more
TL;DR: SRT appears to be a safe and reasonably effective technique to treat brain metastases deemed less suitable for SRS, though dose intensification strategies may further improve local control.
49
Linear accelerator-based stereotactic radiosurgery for brainstem metastases: the Dana-Farber/Brigham and Women's Cancer Center experience.
Paul J. Kelly,Y Lin,Alvin Y.C. Yu,Alexander E. Ropper,Paul L. Nguyen,Karen J. Marcus,Fred Hacker,Stephanie E. Weiss +7 more
TL;DR: Linac-based SRS for small volume brainstem metastases using a median dose of 13 Gy is associated with acceptable local control and low morbidity and trended toward statistical significance for overall survival.
42
Quantifying ITV instabilities arising from 4DCT: a simulation study using patient data
TL;DR: The locations of gold fiducial markers implanted in lung tumours of eight patients to represent tumour motion are used in a simulation of a four-slice CT scanner to generate the ITV for 10, 20 and 30 mm diameter model tumours.