Franziska Presber
Charité
3 Papers
75 Citations
Franziska Presber is an academic researcher from Charité. The author has contributed to research in topics: ELISPOT & Transplantation. The author has an hindex of 3, co-authored 3 publications.
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Papers
High levels of CMV-IE-1-specific memory T cells are associated with less alloimmunity and improved renal allograft function
Peter Nickel,Gantuja Bold,Franziska Presber,Didier Biti,Nina Babel,Stephanie Kreutzer,Johann Pratschke,Constanze Schönemann,Florian Kern,Hans-Dieter Volk,Petra Reinke +10 more
TL;DR: No evidence for heterologous immunity could be found in patients with high levels of CMV-specific T cells, and the importance of immediate early antigens (IE) as targets for T-cell immunity to CMV is emphasized.
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Modified ELISPOT technique — Highly significant inverse correlation of post-Tx donor-reactive IFNγ-producing cell frequencies with 6 and 12 months graft function in kidney transplant recipients☆
Bele Johanna Näther,Peter Nickel,Gantuja Bold,Franziska Presber,Constanze Schönemann,Johann Pratschke,Hans-Dieter Volk,Petra Reinke +7 more
TL;DR: The results suggest that the modified donor-reactive ELISPOT approach might provide a useful surrogate marker for renal transplant outcome with possible utility especially in T-lymphopenic patients.
Enzyme-linked immunosorbent spot assay for donor-reactive interferon-gamma-producing cells identifies T-cell presensitization and correlates with graft function at 6 and 12 months in renal-transplant recipients.
Peter Nickel,Franziska Presber,Gantuja Bold,Didier Biti,Constanze Schönemann,Stefan G. Tullius,Hans-Dieter Volk,Petra Reinke +7 more
TL;DR: The pretransplant ELISPOT assay might be useful to identify T-cell presensitized patients, who are at heightened risk for severe early acute rejection, and an analysis of ELisPOT donor-reactive cells during the early posttransplant period might allow an identification of patients at risk for immune-mediated graft deterioration.