Francisco J. Ayala
University of California, Irvine
540 Papers
10.8K Citations
Francisco J. Ayala is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Population & Biology. The author has an hindex of 87, co-authored 537 publications. Previous affiliations of Francisco J. Ayala include University of Valencia & University of California.
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Papers
Complex Interplay of Evolutionary Forces in the ladybird Homeobox Genes of Drosophila melanogaster
TL;DR: It is argued that balancing selection impacts some synonymous sites of the lbe gene and interplay of balancing and directional selection may be a general feature of molecular evolution in Drosophila and other eukaryote genomes.
Linkage disequilibrium in natural and experimental populations of Drosophila melanogaster.
TL;DR: Linkage disequilibrium in Drosophila melanogaster populations is most likely due to natural selection acting on the allozymes, or on loci very tightly linked to them, or as a consequence of population bottlenecks.
Pseudogenes are not pseudo any more.
TL;DR: The regulatory mechanisms of pseudogenes at the post-transcriptional level are discussed and new ideas toward understanding the evolution of these are advanced, sometimes called “garbage genes” or “junk DNA,” seeking to stimulate the interest of scientists and additional research on the subject.
Malaria continues to select for sickle cell trait in
Central Africa,Eric Elguero,Lucrèce M. Délicat-Loembet,Virginie Rougeron,Céline Arnathau,Benjamin Roche,Pierre Becquart,Jean-Paul Gonzalez,Dieudonné Nkoghe,Lucas Sica,Eric M. Leroy,Patrick Durand,Francisco J. Ayala,Benjamin Ollomo,François Renaud,Franck Prugnolle +15 more
- 01 Jan 2015
TL;DR: Using an extensive cohort of 3,959 persons, distributed over the entire Gabonese Republic, this study shows that P. falciparum malaria continues to exert strong selective pressure in favor of the sickle cell allele, showing that malaria remains a selective factor in current human populations, despite the progress of medicine and the actions undertaken to fight this disease.
Genetic differentiation between species of the genus speyeria (lepidoptera: nymphalidae).
TL;DR: The amount of genetic variation in natural populations of 10 different species, the degree of genetic differentiation between local populations and the processes responsible for such differentiation, and the amount of differentiaton between the subspecies and between the species of Speyeria are investigated.