Francine Deschesnes
Laval University
23 Papers
323 Citations
Francine Deschesnes is an academic researcher from Laval University. The author has contributed to research in topics: Asthma & Allergy. The author has an hindex of 15, co-authored 23 publications.
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Papers
Inhibitory effects of an anti-IgE antibody E25 on allergen-induced early asthmatic response
Louis-Philippe Boulet,Kenneth R. Chapman,Johanne Côté,Sanjay Kalra,Rajesh Bhagat,Veronica A. Swystun,Michel Laviolette,Laura D. Cleland,Francine Deschesnes,John Q. Su,Arthur Devault,Robert B. Fick,Donald W. Cockcroft +12 more
TL;DR: The inhibitory effects of rhuMAb-E25 on allergen-induced EAR suggest that it may be an effective, novel antiallergic treatment for asthma.
417
Smoking and Asthma: Clinical and Radiologic Features, Lung Function, and Airway Inflammation
Louis-Philippe Boulet,Catherine Lemière,Francine Archambault,Guy Carrier,Marie Claire Descary,Francine Deschesnes +5 more
TL;DR: In this paper, the authors compared clinical, physiologic, radiologic, and airway inflammatory features of 22 smoking asthma patients (cigarette smoking history, 14.0 ± 7.6 pack-years [mean ± SD]) and 27 nonsmoking asthma patients.
211
Near-fatal asthma: clinical and physiologic features, perception of bronchoconstriction, and psychologic profile.
TL;DR: The authors studied 19 subjects with asthma, 6 months to 5 years after a near-fatal (NF) episode of asthma, who had the following evaluation: questionnaire on the characteristics of their asthma, spirometry, morning and evening measurements of peak expiratory flow rates (PEFR) with daily recordings of asthma symptoms for 4 weeks, and psychometric evaluation with the Minnesota Multiphasic Personality Inventory.
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Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects
Gail M. Gauvreau,Louis-Philippe Boulet,Christine Schmid-Wirlitsch,Johanne Côté,MyLinh Duong,Kieran J. Killian,Joanne Milot,Francine Deschesnes,Tara X. Strinich,Richard M. Watson,Dirk Bredenbröker,Paul M. O'Byrne +11 more
TL;DR: The observed attenuation of sputum eosinophils and neutrophils demonstrates the anti-inflammatory properties of PDE4 inhibition and supports the roles of both cell types in the development of late phase bronchoconstriction and AHR.
Evaluation of single-dose inhaled corticosteroid activity with an allergen challenge model.
Kidney Jc,L.-P. Boulet,F. E. Hargreave,Francine Deschesnes,Veronica A. Swystun,Paul M. O'Byrne,Choudry N,M M Morris,Barbara Jennings,Andersson N,Andreasson A,Donald W. Cockcroft +11 more
TL;DR: The allergen-induced LAR model was able to differentiate a single dose of an active inhaled corticosteroid from placebo and a highly potent inhaled steroid from a weak inhaled Corticosteroids.
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