Francesco Moccia
University of Pavia
196 Papers
747 Citations
Francesco Moccia is an academic researcher from University of Pavia. The author has contributed to research in topics: Chemistry & Biology. The author has an hindex of 41, co-authored 163 publications. Previous affiliations of Francesco Moccia include University College London & University of Queensland.
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Papers
The Emerging Role of N-Methyl-D-Aspartate (NMDA) Receptors in the Cardiovascular System: Physiological Implications, Pathological Consequences, and Therapeutic Perspectives
TL;DR: In this paper , the authors survey the most recent information available regarding the distribution and function of NMDARs within the cardiovascular system, including their involvement in the modulation of heart rate and cardiac rhythm, regulation of arterial blood pressure, in the regulation of cerebral blood flow, and in the blood-brain barrier permeability.
Supporting data on in vitro cardioprotective and proliferative paracrine effects by the human amniotic fluid stem cell secretome.
Carolina Balbi,Kirsten Lodder,Ambra Costa,Silvia Moimas,Francesco Moccia,Tessa van Herwaarden,Vittorio Rosti,Francesca Campagnoli,Agnese Palmeri,Pierangela De Biasio,Francesco Santini,Mauro Giacca,Marie-José Goumans,Lucio Barile,Anke M. Smits,Sveva Bollini +15 more
TL;DR: This dataset illustrates the in vitro paracrine effect exerted by the human amniotic fluid stem cell secretome on rodent neonatal cardiomyocytes, human endothelial progenitors and different subsets of cardiac progenitor cells.
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The human amniotic fluid stem cell secretome triggers intracellular Ca2+ oscillations, NF-κB nuclear translocation and tube formation in human endothelial colony-forming cells
Valentina Balducci,Pawan Faris,Carolina Balbi,Ambra Costa,Sharon Negri,Vittorio Rosti,Sveva Bollini,Francesco Moccia +7 more
TL;DR: In this article, the secretome obtained by amniotic fluid-derived stem cells undergoing hypoxic preconditioning induced intracellular Ca2+ oscillations by promoting extracellular Ca 2+ entry through Transient Receptor Potential Vanilloid 4 (TRPV4).
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A bidirectional crosstalk between glioblastoma and brain endothelial cells potentiates the angiogenic and proliferative signaling of sphingosine-1-phosphate in the glioblastoma microenvironment.
Loubna Abdel Hadi,V. Anelli,Laura Guarnaccia,Stefania Elena Navone,Matteo Beretta,Francesco Moccia,Cristina Tringali,Vasile Urechie,Rolando Campanella,Giovanni Marfia,Laura Riboni +10 more
TL;DR: The results envision glioblastoma-endothelial crosstalk as a multi-compartmental strategy to enforce pro-tumoral sphingosine-1-phosphate signaling in the gliOBlastoma microenvironment.
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Ca2+ signalling and membrane current activated by cADPr in starfish oocytes
Francesco Moccia,Gilda A. Nusco,Dmitri Lim,Emanuela Ercolano,Gianni Gragnaniello,Euan R. Brown,Luigia Santella +6 more
TL;DR: It is suggested that cADPr activates a Ca2+ wave by releasing Ca 2+ from intracellular ryanodine receptors and that the rise in [Ca2+]i triggers a non-selective monovalent cation current that does not seem to contribute to the global Ca2- elevation.
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