Francesca L. Sciacca
Mario Negri Institute for Pharmacological Research
47 Papers
596 Citations
Francesca L. Sciacca is an academic researcher from Mario Negri Institute for Pharmacological Research. The author has contributed to research in topics: Biology & Cell adhesion molecule. The author has an hindex of 23, co-authored 43 publications. Previous affiliations of Francesca L. Sciacca include Academy for Urban School Leadership.
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Papers
Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells.
Nives Jonjić,Giuseppe Peri,Sergio Bernasconi,Francesca L. Sciacca,Francesco Colotta,Pier Giuseppe Pelicci,Luisa Lanfrancone,Alberto Mantovani +7 more
TL;DR: Results indicate that mesothelial cells can express a set of adhesion molecules and chemotactic cytokines overlapping with, but distinct from, that expressed in vascular endothelium, and that these are functionally relevant for interacting with mononuclear phagocytes.
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Expression of monocyte chemotactic protein-1 by monocytes and endothelial cells exposed to thrombin
Francesco Colotta,Francesca L. Sciacca,Marina Sironi,Walter Luini,Marie J. Rabiet,Alberto Mantovani +5 more
TL;DR: Induction of a chemotactic cytokine for monocytes by thrombin points to the importance of this enzyme in regulating inflammatory processes and further indicates that hemostasis, inflammation, and immunity are strictly interconnected processes.
231
Molecular Mechanisms Generating and Stabilizing Terminal 22q13 Deletions in 44 Subjects with Phelan/McDermid Syndrome.
Maria Clara Bonaglia,Roberto Giorda,Silvana Beri,Cristina De Agostini,Francesca Novara,Marco Fichera,Lucia Grillo,Ornella Galesi,Annalisa Vetro,Roberto Ciccone,Maria Teresa Bonati,Sabrina Giglio,Sabrina Giglio,Renzo Guerrini,Sara Osimani,Susan Marelli,Claudio Zucca,Rita Grasso,Renato Borgatti,Elisa Mani,Cristina Motta,Massimo Molteni,Corrado Romano,Donatella Greco,Santina Reitano,Anna Baroncini,Elisabetta Lapi,Elisabetta Lapi,Antonella Cecconi,Giulia Arrigo,Maria Grazia Patricelli,Chiara Pantaleoni,Stefano D'Arrigo,Daria Riva,Francesca L. Sciacca,Bernardo Dalla Bernardina,Leonardo Zoccante,Francesca Darra,Cristiano Termine,Emanuela Maserati,Stefania Bigoni,Emanuela Priolo,Armand Bottani,Stefania Gimelli,Frédérique Béna,Alfredo Brusco,Eleonora Di Gregorio,Irene Bagnasco,Ursula Giussani,Lucio Nitsch,Pierluigi Politi,María Luisa Martínez-Frías,María Luisa Martínez-Frías,Maria Luisa Martínez-Fernández,Maria Luisa Martínez-Fernández,Nieves Martínez Guardia,Anna Bremer,Britt-Marie Anderlid,Orsetta Zuffardi +58 more
TL;DR: The progressive clinical deterioration observed throughout the longitudinal medical history of three subjects over forty years supports the hypothesis of a role for SHANK3 haploinsufficiency in neurological deterioration, in addition to its involvement in the neurobehavioral phenotype of PMS.
Regulation of endothelial and mesothelial cell function by interleukin-13: selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production.
Marina Sironi,Francesca L. Sciacca,Cristian Matteucci,M. Conni,Annunciata Vecchi,Sergio Bernasconi,A Minty,D. Caput,P Ferrara,Francesco Colotta +9 more
TL;DR: IL-13 elicits a spectrum of responses in vascular endothelium remarkably similar to that of IL-4 and IL-10, which may play an important role in the induction and expression of Th2-dependent responses.
123
Relevance of interleukin 1 receptor antagonist intron 2 polymorphism in Italian MS patients.
Francesca L. Sciacca,Cinzia Ferri,Koen Vandenbroeck,Fabrizio Veglia,Claudio Gobbi,F. Martinelli,Diego Franciotta,M. Zaffaroni,M. Marrosu,Gianvito Martino,Vittorio Martinelli,G. Comi,N. Canal,L.M.E. Grimaldi +13 more
TL;DR: It is concluded that an IL-1Ra gene polymorphism is associated with occurrence of disease and clinical course variability in Italian MS patients.
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