Frances M. Cowan
Liverpool School of Tropical Medicine
489 Papers
3.7K Citations
Frances M. Cowan is an academic researcher from Liverpool School of Tropical Medicine. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 76, co-authored 456 publications. Previous affiliations of Frances M. Cowan include University of Zimbabwe & University of Bristol.
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Papers
Hypoglycaemia and neonatal brain injury
TL;DR: In this model infants at risk of neurological sequelae from hypoglycaemia are identified, and interventions to raise the BG are recommended at specified thresholds, with the caveat that acute neurological dysfunction in association with low BG at any level should prompt urgent investigation and treatment.
Field evaluation of diagnostic accuracy of an oral fluid rapid test for HIV, tested at point-of-service sites in rural Zimbabwe.
TL;DR: The results showed the OraQuick ADVANCE Rapid HIV-1/2 Antibody test to be 100% accurate in determining HIV status, performed well in field settings, and can be considered suitable for use in epidemiologic surveys aiming to estimate HIV prevalence in general populations.
Neonatal cerebral infarction and visual function at school age
Eugenio Mercuri,Shirley Anker,Andrea Guzzetta,A. L. Barnett,Leena Haataja,Mary A. Rutherford,Frances M. Cowan,Lilly Dubowitz,Oliver Braddick,Janette Atkinson +9 more
TL;DR: Abnormality of visual function is not common in children who had neonatal infarction and, when present, tends to be associated with hemiplegia and more extensive lesions.
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Novel missense mutations in the glycine receptor β subunit gene (GLRB) in startle disease
Victoria M. James,Anna Bode,Seo-Kyung Chung,Jennifer Gill,Maartje Nielsen,Frances M. Cowan,Mihailo Vujic,Mihailo Vujic,Rhys H. Thomas,Mark I. Rees,Kirsten Harvey,Angelo Keramidas,Maya Topf,Ieke B. Ginjaar,Joseph W. Lynch,Robert J. Harvey +15 more
TL;DR: A leak conductance associated with spontaneous GlyR activity in cells expressing α1βL285R GlyRs was identified and may represent an example of incomplete dominance in startle disease, providing a potential genetic explanation for the ‘minor’ form of hyperekplexia.
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•Journal Article
MR imaging quantification of cerebellar growth following hypoxic-ischemic injury to the neonatal brain
TL;DR: Infants with focal infarction of the cerebral hemisphere had an apparently normal pattern of growth in both cerebellar hemispheres, however, in infants with severe basal ganglia and thalamic lesions, Cerebellar growth was reduced, and the vermis showed little or no growth during the first year after birth.
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