Florian Bea
University Hospital Heidelberg
4 Papers
Florian Bea is an academic researcher from University Hospital Heidelberg. The author has contributed to research in topics: Proinflammatory cytokine & Myocyte. The author has an hindex of 4, co-authored 4 publications.
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Papers
Intracoronary Delivery of Injectable Bioabsorbable Scaffold (IK-5001) to Treat Left Ventricular Remodeling After ST-Elevation Myocardial Infarction A First-in-Man Study
Norbert Frey,Axel Linke,Tim Süselbeck,Jochen Müller-Ehmsen,Paul Vermeersch,Danny Schoors,Mark Rosenberg,Florian Bea,Shmuel Tuvia,Jonathan Leor +9 more
TL;DR: This first-in-man pilot study shows that intracoronary deployment of an IK-5001 scaffold is feasible and well tolerated and promoted the initiation of a multicenter, randomized controlled trial to confirm the safety and efficacy of this new approach in high-risk patients after ST-segment–elevation myocardial infarction.
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FGF-inducible 14-kDa protein (Fn14) is regulated via the RhoA/ROCK kinase pathway in cardiomyocytes and mediates nuclear factor-kappaB activation by TWEAK.
Emmanuel Chorianopoulos,Thomas Heger,Matthias Lutz,Derk Frank,Florian Bea,Hugo A. Katus,Norbert Frey +6 more
TL;DR: Evidence is provided of a stress-induced regulation of the TWEAK/Fn14 axis in cardiomyocytes implying a role of the Rho/ROCK pathway in cardiac remodeling and little is known about the functional role of Fn14.
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1-year outcome of TRIAS HR (TRI-stent adjudication study-high risk of restenosis) a multicenter, randomized trial comparing genous endothelial progenitor cell capturing stents with drug-eluting stents.
Margo Klomp,Marcel A.M. Beijk,Chetan Varma,Jacques J. Koolen,Emmanuel Teiger,Gert Richardt,Florian Bea,Nan van Geloven,Niels J.W. Verouden,Yu Kwan Chan,Pier Woudstra,Peter Damman,Jan G.P. Tijssen,Robbert J. de Winter +13 more
TL;DR: Within 1 year, inhibition of intimal hyperplasia by the ECS is not sufficiently strong to compete with DES in terms of restenosis prevention in patients/lesions with a high risk of restENosis.
The role of endothelial cell biology in endocarditis.
TL;DR: Insight is given into current knowledge of the pathogenesis of endocarditis with a focus on the role of the endothelium, which involves the damage and disturbance of endothelial function and the formation of associated “vegetation”.