Florenz Sasse
Leibniz University of Hanover
192 Papers
2.5K Citations
Florenz Sasse is an academic researcher from Leibniz University of Hanover. The author has contributed to research in topics: Myxobacteria & Chemistry. The author has an hindex of 42, co-authored 188 publications. Previous affiliations of Florenz Sasse include University of Tübingen & University of Stuttgart.
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Papers
Iodine‐Promoted Oxidative Conversion of o‐Vinyl Diaryl Ketones into o‐Acetyl Diaryl Ketones, Synthesis of 1‐Methyl‐4‐arylphthalazines as Analogues of Podophyllotoxin
TL;DR: In this paper, the metal-free oxidation of o-vinyl diaryl ketones in the presence of molecular iodine or N-iodosuccinimide was described.
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Screening of small molecules affecting mammalian P-body assembly uncovers links with diverse intracellular processes and organelle physiology.
Javier Martínez,Gemma Pérez-Vilaró,Yazh Muthukumar,Nicoletta Scheller,Tatjana Hirsch,Randi Diestel,Heinrich Steinmetz,Rolf Jansen,Ronald Frank,Florenz Sasse,Andreas Meyerhans,Juana Díez +11 more
TL;DR: An automated cell-based assay platform is established and from a unique library of compounds derived from myxobacteria, 30 specifically inhibited P-body assembly, showing the strongest effect of Gephyronic acid A, a eukaryotic protein synthesis inhibitor.
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Identification of StiR, the first regulator of secondary metabolite formation in the myxobacterium Cystobacter fuscus Cb f17.1.
TL;DR: A novel positive regulator (stiR) of stigmatellin production was identified after transposon recovery and this strain was shown to be equally effected in natural product biosynthesis.
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Argyrins, Immunosuppressive Cyclic Peptides from Myxobacteria. Part 1. Production, Isolation, Physico-Chemical and Biological Properties.
TL;DR: All argyrins had slight antibiotic activity, especially against Pseudomonas sp.
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Synthesis and Biological Evaluation of Apicularen A Analogues
TL;DR: In this paper, the apicularen A analogues 21, 29, 34, 38, and 41 were derived from amide anions and propanal derivatives containing benzolactone components.
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