Fengxia Yang
Guangzhou Medical University
9 Papers
3 Citations
Fengxia Yang is an academic researcher from Guangzhou Medical University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 1, co-authored 6 publications. Previous affiliations of Fengxia Yang include Sun Yat-sen University.
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Papers
Multi-omic profiling of plasma reveals molecular alterations in children with COVID-19.
Chong Wang,Chong Wang,Xufang Li,Wanshan Ning,Sitang Gong,Fengxia Yang,Chunxiao Fang,Yu Gong,Di Wu,Muhan Huang,Yujie Gou,Shanshan Fu,Yujie Ren,Yujie Ren,Ruyi Yang,Yang Qiu,Yu Xue,Yi Xu,Xi Zhou,Xi Zhou +19 more
TL;DR: In this paper, a machine learning-based pipeline named inference of biomolecular combinations with minimal bias (iBM) was developed to prioritize proteins and metabolites strongly altered in COVID-19-children, and experimentally validated the predictions.
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Echovirus 11 infection induces pyroptotic cell death by facilitating NLRP3 inflammasome activation
Chong Wang,Ruyi Yang,Fengxia Yang,Yang Han,Yujie Ren,Xiaobei Xiong,Xingyun Wang,Yidan Bi,Lijun Li,Yang Qiu,Yin Xu,Xi Zhou +11 more
TL;DR: A mechanism by which Echo 11 induces inflammatory responses by activating NLRP3 inflammasome is demonstrated, providing novel insights into the pathogenesis of ECHO 11 infection.
Clinical and genetic characterization of pediatric patients with progressive familial intrahepatic cholestasis type 3 (PFIC3): identification of 14 novel ABCB4 variants and review of the literatures
Rongbing Chen,Fengxia Yang,Yanfang Tan,Mei Deng,Hua Li,Yin Xu,Wenxiang Ouyang,Yuan-Zong Song +7 more
TL;DR: In this article , the authors investigated the ABCB4 genotypic and clinical phenotypic features of PFIC3 patients, and 14 new variants were detected, including eight likely pathogenic and six pathogenic.
Multi-Omic Profiling of Plasma Identify Biomarkers and Pathogenesis of COVID-19 in Children
Chong Wang,Xufang Li,Wanshan Ning,Sitang Gong,Fengxia Yang,Chunxiao Fang,Yu Gong,Di Wu,Muhan Huang,Yujie Gou,Shanshan Fu,Yujie Ren,Ruyi Yang,Yang Qiu,Yu Xue,Yi Xu,Xi Zhou +16 more
TL;DR: The finding of a strong antagonism of deleterious and protective effects provided new insights on the mechanism and pathogenesis of CC cases that mostly undergo mild symptoms, and could serve as candidate drug targets or therapeutic agents of COVID-19.
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Multi-Omic Profiling of Plasma Identify Biomarkers and Pathogenesis of COVID-19 in Children
Chong Wang,Xufang Li,Wanshan Ning,Sitang Gong,Fengxia Yang,Chunxiao Fang,Yu Gong,Di Wu,Muhan Huang,Yujie Gou,Shanshan Fu,Yujie Ren,Ruyi Yang,Yang Qiu,Yu Xue,Yi Xu,Xi Zhou +16 more
TL;DR: In this article, the authors conducted the plasma proteomic and metabolomic profiling of a cohort of COVID-19 pediatric patients with mild symptoms and found that numerous proteins and metabolites involved in immune as well as anti-inflammatory processes were upregulated on a larger scale in children than in adults.