Fenglin Li
Zhejiang University
38 Papers
20 Citations
Fenglin Li is an academic researcher from Zhejiang University. The author has contributed to research in topics: Myeloid leukemia & Medicine. The author has an hindex of 4, co-authored 16 publications.
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Papers
High PARP-1 expression predicts poor survival in acute myeloid leukemia and PARP-1 inhibitor and SAHA-bendamustine hybrid inhibitor combination treatment synergistically enhances anti-tumor effects.
Xia Li,Chenying Li,Jingrui Jin,Jinghan Wang,Jiansong Huang,Zhixin Ma,Xin Huang,Xiao He,Yile Zhou,Yu Xu,Mengxia Yu,Shujuan Huang,Xiao Yan,Fenglin Li,Jiajia Pan,Yungui Wang,Yongping Yu,Jie Jin +17 more
TL;DR: The synergistic effects of PARP inhibitor BMN673 in combination with SAHA-bendamustine hybrid, NL101, provide a new therapeutic strategy against AML and predicts poor survival in CN-AML patients.
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The global burden and attributable risk factors of chronic lymphocytic leukemia in 204 countries and territories from 1990 to 2019: analysis based on the global burden of disease study 2019
TL;DR: In this paper , the authors evaluated the disease burden of CLL at global, regional, and national levels from 1990 to 2019, and studied the influence of demographic factors and performed risk factor analysis.
Leukemia stem cell-bone marrow microenvironment interplay in acute myeloid leukemia development.
TL;DR: In this paper, the authors summarized the alterations in the bidirectional interplay between hematopoietic cells and BMM, and pointed out the key role of these alterations in pathogenesis and chemotherapy resistance of acute myeloid leukemia (AML).
Abivertinib inhibits megakaryocyte differentiation and platelet biogenesis.
Jiansong Huang,Xin Huang,Yang Li,Xia Li,Jinghan Wang,Fenglin Li,Xiao Yan,Huanping Wang,Yungui Wang,Xiangjie Lin,Jifang Tu,Daqiang He,Wenle Ye,Min Yang,Jie Jin +14 more
TL;DR: Abivertinib, a third-generation tyrosine kinase inhibitor, is originally designed to target epidermal growth factor receptor (EGFR)-activating mutations as discussed by the authors, and it has shown promising antitumor activity and a well-tolerated safety profile in patients with non-small-cell lung cancer.
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Spermatogenesis associated serine rich 2 like plays a prognostic factor and therapeutic target in acute myeloid leukemia by regulating the JAK2/STAT3/STAT5 axis
Fenglin Li,Wenle Ye,Yiyi Yao,Wenwen Wei,Haihui Zhuang,Chenying Li,Xia Li,Qing Ling,Chao Hu,Xin Huang,Yu Qian,Shihui Mao,Jiansong Huang,Ying Liu,Jie Jin +14 more
TL;DR: In this paper , Spermatogenesis associated serine rich 2 like (SPATS2L) was highly expressed in homoharringtonine (HHT) resistant acute myeloid leukemia (AML) cell lines.