Feng Zheng
Chinese Academy of Sciences
14 Papers
104 Citations
Feng Zheng is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Claisen rearrangement & Thionucleosides. The author has an hindex of 8, co-authored 14 publications.
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Papers
Synthesis of Trifluoromethylated and gem-Difluoromethylenated Biologically Interesting Compounds from Fluorine-Containing Synthons
Feng-Ling Qing,Feng Zheng +1 more
TL;DR: A number of fluorinated versatile building blocks (synthons) were developed for the synthesis of trifluoromethylated and gem-difluorsylenated biologically interesting compounds as discussed by the authors.
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Synthesis of γ-monofluorinated goniothalamin analogues via regio- and stereoselective ring-opening hydrofluorination of epoxide.
TL;DR: A stereoselective synthesis of the biologically interesting γ-monofluorinated goniothalamin analogue 2a was described and the chiral hydroxypropynyl fluorohydrin 15 was used as a valuable building block for preparation of a range of α,β-unsaturated δ-lactones.
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Synthesis of l-β-3‘-Deoxy-3‘,3‘-difluoro-4‘-thionucleosides
TL;DR: In this paper, an efficient route to l-β-3-deoxy-3,3-difluorothiofuranose skeleton was described, highlighting the installation of the thioacetyl group in high efficiency.
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Synthesis of 2′,3′-dideoxy-6′-fluorocarbocyclic nucleosides via Reformatskii–Claisen rearrangement
TL;DR: In this article, the synthesis of carbocyclic nucleosides using reformatskii-Claisen rearrangement of allyl bromofluoroacetate was described.
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Synthesis of monofluorinated isofagomine analogues and evaluation as glycosidase inhibitors
TL;DR: The straightforward synthesis of monofluorinated isofagomine analogues 1-3 was described, and the 3S,4R,5R isomer 3 has been found to be a potent inhibitor against beta-glucosidase from almonds with K(i) value of 11.9 mu.
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