Feng-qi Yan
Fourth Military Medical University
14 Papers
7 Citations
Feng-qi Yan is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 2 publications.
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Papers
The Novel Nrf2 Activator Omaveloxolone Regulates Microglia Phenotype and Ameliorates Secondary Brain Injury after Intracerebral Hemorrhage in Mice
Libin Hu,Yang Cao,Huaijun Chen,Lei Xu,Qiguo Yang,Hang Zhou,Jianru Li,Qian Yu,Zhangqi Dou,Yin Li,Feng-qi Yan,Fuyi Liu,Gao Chen +12 more
TL;DR: Omav modulated microglial polarization by activating Nrf2 and inhibiting ROS generation in ICH models, suggesting that it might be a promising drug candidate for the treatment of ICH.
Neutrophil-like pH-responsive pro-efferocytic nanoparticles improve neurological recovery by promoting erythrophagocytosis after intracerebral hemorrhage
Linfeng Fan,Lulu Jin,Tianchi Tang,Yong Xia Zheng,Zihang Chen,Haopu Lin,Chao Ding,Tingting Wang,Huaijun Chen,Yinghan Guo,Chaoran Xu,Hang Zhou,Xinyan Wu,Xiongjie Fu,Feng-qi Yan,Zhengwei Mao,Gao Chen +16 more
TL;DR: This biomimetic nanomedicine is envisaged to offer an encouraging strategy to effectively promote hematoma and inflammation resolution, consequently alleviate ICH progression.
Metformin Alleviates Neuroinflammation Following Intracerebral Hemorrhage in Mice by Regulating Microglia/Macrophage Phenotype in a Gut Microbiota-Dependent Manner
Xiaobo Yu,Xiongjie Fu,Xinyan Wu,Wenwen Tang,Lei Xu,Libin Hu,Chaoran Xu,Hang Zhou,Guoyang Zhou,Jianru Li,Shenglong Cao,Jiang Liu,Feng-qi Yan,Lin Wang,Fuyi Liu,Gao Chen +15 more
TL;DR: It is found that Met treatment substantially alleviated neurological dysfunction and reduced neuroinflammation by inhibiting pro-inflammatory polarization of microglia/macrophages in mice with ICH, and is a promising therapeutic agent for neuro inflammation owing to ICH-induced imbalance of the gut microbiota.
Probenecid-Blocked Pannexin-1 Channel Protects Against Early Brain Injury via Inhibiting Neuronal AIM2 Inflammasome Activation After Subarachnoid Hemorrhage
TL;DR: Pannexin-1 channel inhibitor probenecid attenuated brain edema and improved neurological dysfunction by reducing AIM2 inflammasome activation and reactive oxygen species (ROS) generation after SAH in rats.
Neutrophil to lymphocyte ratio predicting poor outcome after aneurysmal subarachnoid hemorrhage: A retrospective study and updated meta-analysis
Yinghan Guo,Jiang Liu,Hanhai Zeng,Lingxin Cai,Tingting Wang,Xinyan Wu,K. Yu,Yong Xia Zheng,Huaijun Chen,Yucong Peng,Xiaobo Yu,Feng-qi Yan,Shenglong Cao,Gao Chen +13 more
TL;DR: Elevated NLR is an independent predictor of poor outcome and DCI occurrence in aSAH and is more reliable in large sample sizes, low NLR cut-off value, multicenter, or prospective studies.