Feng Lu
Jiangsu University
5 Papers
Feng Lu is an academic researcher from Jiangsu University. The author has contributed to research in topics: Melanoma & Metastasis. The author has an hindex of 3, co-authored 5 publications.
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Papers
Long non-coding RNA HOTAIR acts as a competing endogenous RNA to promote malignant melanoma progression by sponging miR-152-3p
TL;DR: HOTAIR promotes the growth and metastasis of melanoma cells by competitively binding miR-152-3p, which functionally liberates c-MET mRNA and results in the activation of the downstream PI3k/Akt/mTOR signaling pathway.
•Journal Article
Long noncoding RNA MIR4435-2HG promotes hepatocellular carcinoma proliferation and metastasis through the miR-22-3p/YWHAZ axis.
TL;DR: The role and mechanism of MIR4435-2HG in malignant progression of HCC was demonstrated and may be used as the prognostic marker and treatment target for the patient with HCC.
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Exosomal miR-106b-5p derived from melanoma cell promotes primary melanocytes epithelial-mesenchymal transition through targeting EphA4
TL;DR: In this article, the role and molecular mechanisms of exosomal miR-106b-5p in melanoma remains unclear, however, it is shown that miR6b5p levels are significantly increased in patients with melanoma.
Long non-coding RNA LINC00520 promotes the proliferation and metastasis of malignant melanoma by inducing the miR-125b-5p/EIF5A2 axis
TL;DR: LINC00520, a new oncogene in melanoma, maybe serve as a survival biomarkers or therapeutic target for melanoma patients and elucidated the role and molecular mechanism in the malignant development of melanoma.
Long noncoding RNA LINC00518 acts as a competing endogenous RNA to promote the metastasis of malignant melanoma via miR-204-5p/AP1S2 axis.
TL;DR: It is found that LINC00518 was significantly upregulated in melanoma tissue, and high LICN00518 level was an independent risk factor for melanoma patients, and may serve as a survival indicator and potential therapeutic target in melan cancer patients.