Feng Lou
Sichuan University
8 Papers
Feng Lou is an academic researcher from Sichuan University. The author has contributed to research in topics: Osteoblast & Bone resorption. The author has an hindex of 5, co-authored 7 publications.
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Papers
Anabolic actions of Notch on mature bone.
Peng Liu,Yilin Ping,Meng Ma,Demao Zhang,Connie Liu,Samir Zaidi,Song Gao,Yaoting Ji,Feng Lou,Fanyuan Yu,Ping Lu,Agnes Stachnik,Mingru Bai,Chengguo Wei,Liaoran Zhang,Ke Wang,Rong Chen,Maria I. New,David W. Rowe,Tony Yuen,Li Sun,Mone Zaidi +21 more
TL;DR: Overexpression of the Notch intracellular domain in mice results in an increase in bone mass, prevents bone loss following ovariectomy and during aging, and promotes fracture healing, and is therefore a potential therapeutic target for conditions of bone loss, including osteoporosis.
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Efficacy of Recombinant Human BMP2 and PDGF-BB in Orofacial Bone Regeneration: A Systematic Review and Meta-analysis.
Feifei Li,Fanyuan Yu,Xueyang Liao,Chenzhou Wu,Yitian Wang,Chunjie Li,Feng Lou,Boer Li,Bei Yin,Chenglin Wang,Ling Ye +10 more
TL;DR: The results indicate that all current concentrations of rhBMP-2 produces insufficient effect on promoting either tooth extraction socket healing, sinus augmentation or reconstruction of alveolar clefts, and recommend concentrations of 0.3 mg/ml rhPDGF-BB only for the healing of tooth extraction sockets.
NUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts
Ling Ye,Feng Lou,Fanyuan Yu,Demao Zhang,Chenglin Wang,Fanzi Wu,Xin Li,Yilin Ping,Xiao Yang,Jing Yang,Dian Chen,Gao Bo,Dingming Huang,Peng Liu +13 more
TL;DR: The team’s studies showed that NUMB and NUMBL suppression inhibits a signaling pathway important to skeletal development and protein synthesis in osteoblasts, though it is raised that further investigations are essential to elucidate the exact mechanistic action of these proteins.
Bioinspired Tumor-Targeting and Biomarker-Activatable Cell-Material Interfacing System Enhances Osteosarcoma Treatment via Biomineralization.
Xiao Yang,Simin Gao,Boguang Yang,Zhinan Yang,Feng Lou,Pei Huang,Pengchao Zhao,Jiaxin Guo,Huapan Fang,Bingyang Chu,Miaomiao He,Raymond Chan,Zuankai Wang,Liming Bian,Kunyu Zhang +14 more
TL;DR: In this paper , a new bioinspired tumor-targeting and enzyme-activatable cell-material interface system based on DDDEEK-pY-phenylboronic acid (SAPPY-PBA) conjugates was reported.
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The role of Wnt7B in the mediation of dentinogenesis via the ERK1/2 pathway.
TL;DR: Wnt7b enhances dentinogenesis by increasing the proliferation and differentiation of dental mesenchymal cells partly through ERK1/2 pathway.