Feng Lan
8 Papers
2 Citations
Feng Lan is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 4, co-authored 7 publications.
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Papers
Intradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy.
Yi You,Yupeng Tian,Zhaogang Yang,Junfeng Shi,Kwang Joo Kwak,Yuhao Tong,Andreanne Poppy Estania,Jianhong Cao,Wei-Hsiang Hsu,Yutong Liu,Chi-Ling Chiang,Benjamin R. Schrank,Kristin Huntoon,DaeYong Lee,Ziwei Li,Yarong Zhao,Huan Zhang,Thomas D Gallup,Jong Hoon Ha,Shiyan Dong,Yifan Wang,Wen-Jing Lu,Eman Bahrani,Ly James Lee,Lesheng Teng,Wen Jiang,Feng Lan,Betty Y.S. Kim,Andrew S. Lee +28 more
TL;DR: In this article , extracellular vesicles (EVs) produced via cellular nanoporation from human dermal fibroblasts, and encapsulating mRNA encoding for extracellular-matrix α1 type-I collagen (COL1A1) induced the formation of collagen-protein grafts and reduced wrinkle formation in the collagen-depleted dermal tissue of mice with photoaged skin.
p55γ degrades RIP3 via MG53 to suppress ischemia-induced myocardial necroptosis and mediates cardioprotection of preconditioning.
Zhenyan Li,Rilei Dai,Min Chen,Lixuan Huang,Kun Zhu,Mingyang Li,Wenting Zhu,Yang Li,N. Xie,Jingchen Li,Li Wang,Feng Lan,C. Cao +12 more
TL;DR: It is revealed that activation of the MG53-RIP3 signal pathway by p55γ protects the heart against I/R-induced necroptosis and underlies IPC-induced cardioprotection and holds potential therapeutic value for treating ischemic heart disease.
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Chemically defined and small molecules-based generation of sinoatrial node-like cells
Xiaojie Hou,Shuhong Ma,Wei Fan,Fang Li,Miaomiao Xu,Chao Yang,Feng Liu,Ying Yan,Juyi Wan,Feng Lan,Bin Liao +10 more
TL;DR: In this article , a chemically defined method for in vitro differentiation of human pluripotent stem cells (hPSCs) into sinoatrial node-like cells (SANLCs) is presented.
Losartan protects human stem cell-derived cardiomyocytes from angiotensin II-induced alcoholic cardiotoxicity
TL;DR: In this article , the authors established an in vitro model of alcoholic cardiomyopathy based on human induced pluripotent stem cell-derived (hiPSC-CMs) and performed RNA-seq analysis.
Generation of a human embryonic stem cell line WAe009-A-79 carrying a long QT syndrome mutation in KCNQ1.
TL;DR: In this paper , the authors established a human embryonic stem cell line (WAe009-A-79) carrying a Long QT syndrome type 1 (LQT1), which is considered to be the most common causative gene of LQT.