Feng Cao
Chinese PLA General Hospital
217 Papers
803 Citations
Feng Cao is an academic researcher from Chinese PLA General Hospital. The author has contributed to research in topics: Medicine & Stem cell. The author has an hindex of 49, co-authored 197 publications. Previous affiliations of Feng Cao include Stanford University & Fourth Military Medical University.
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Papers
Melatonin protects cardiac microvasculature against ischemia/reperfusion injury via suppression of mitochondrial fission-VDAC1-HK2-mPTP-mitophagy axis.
Hao Zhou,Ying Zhang,Shunying Hu,Chen Shi,Pingjun Zhu,Qiang Ma,Qinhua Jin,Feng Cao,Feng Tian,Yundai Chen +9 more
TL;DR: It is confirmed that melatonin protects cardiac microvasculature against IRI and the underlying mechanism may be attributed to the inhibitory effects of melatonin on mitochondrial fission‐VDAC1‐HK2‐mPTP‐mitophagy axis via activation of AMPKα.
348
Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts
Rutger-Jan Swijnenburg,Sonja Schrepfer,Johannes A. Govaert,Feng Cao,Katie Ransohoff,Ahmad Y. Sheikh,Munif Haddad,Andrew J. Connolly,Mark M. Davis,Robert C. Robbins,Joseph C. Wu +10 more
TL;DR: It is shown that immunosuppressive drug regimens can mitigate the anti-hESC immune response and that a regimen of combined tacrolimus and sirolimus therapies significantly prolongs survival of hESCs for up to 28 days.
319
The role of the autophagy in myocardial ischemia/reperfusion injury.
TL;DR: The functional significance of autophagy in cardiac ischemia reperfusion injury is reviewed and underlying signaling pathways are discussed to discuss underlying signalling pathways.
296
Ripk3 induces mitochondrial apoptosis via inhibition of FUNDC1 mitophagy in cardiac IR injury.
Hao Zhou,Pingjun Zhu,Jun Guo,Nan Hu,Shuyi Wang,Dandan Li,Shunying Hu,Jun Ren,Feng Cao,Yundai Chen +9 more
TL;DR: This study confirms the promotive effect of Ripk3 on mitochondria-mediated apoptosis via inhibition of FUNDC1-dependent mitophagy in cardiac IRI.
282
Melatonin Ameliorates the Progression of Atherosclerosis via Mitophagy Activation and NLRP3 Inflammasome Inhibition
Sai Ma,Jiangwei Chen,Jing Feng,Ran Zhang,Miaomiao Fan,Dong Han,Xiang Li,Congye Li,Jun Ren,Yabin Wang,Feng Cao +10 more
TL;DR: It is demonstrated that melatonin prevented atherosclerotic progression, at least in part, via inducing mitophagy and attenuating NLRP3 inflammasome activation, which was mediated by the Sirt3/FOXO3a/Parkin signaling pathway.
219