Fen Chen
Hubei University of Medicine
5 Papers
Fen Chen is an academic researcher from Hubei University of Medicine. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 1, co-authored 1 publications.
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Papers
Zinc finger protein 671 has a cancer-inhibiting function in colorectal carcinoma via the deactivation of Notch signaling.
TL;DR: Zinc finger protein 671 (ZNF671) has been described as a vital cancer inhibitor in multiple neoplasms, yet the functional roles of ZNF671 in colorectal carcinoma (CRC) remain unresolved as discussed by the authors .
5
Journal Article
CircCCNB1 Knockdown Blocks the Progression of Cervical Cancer by Acting as Competing Endogenous RNA in the miR-370-3p/SOX4 Pathway.
TL;DR: In this article , the role of circRNA cyclin B1 (circCCNB1) in cervical cancer development was determined by quantifying quantitative real-time PCR (qPCR) and functional experiments, including colony formation assay, EdU assay, transwell assay and flow cytometry assay.
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MiR-497-3p induces Premature ovarian failure by targeting KLF4 to inactivate Klotho/PI3K/AKT/mTOR signaling pathway.
Yuhan Zhou,Feifei Yuan,Chunliang Jia,Fen Chen,Fei Li,Lingyu Wang +5 more
TL;DR: MiR-497-3p promotes DNA damage and apoptosis in CTX-treated KGN cells by targeting KLF4 to downregulate Klotho and inactivate the PI3K/AKT/mTOR signaling pathway.
ERG the modulates Warburg effect and tumor progression in cervical cancer.
TL;DR: This study found that ectopic expression of ERG enhanced the capacity of aerobic glycolysis and increased glucose uptake, lactate production, and ATP generation, and suggested that ERG plays a potential role in the progression of cervical cancer, and could serve as a novel biomarker and potential therapeutic target in cervical cancer.
YAP-activated SATB2 is a coactivator of NRF2 that amplifies anti-oxidative capacity and promotes tumor progression in renal cell carcinoma.
Jun Jin,Fen Chen,Wenfang He,Li Zhao,Bo Li,Danna Zheng,Li Chen,Hongchao He,Qi He +8 more
TL;DR: In this article , upregulation of the nuclear matrix-associated protein SATB2 in renal cell carcinoma (RCC) samples was reported, which correlated with poor prognosis.