Felix Evers
Radboud University Nijmegen
9 Papers
Felix Evers is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Computer science & Plasmodium falciparum. The author has an hindex of 3, co-authored 3 publications.
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Papers
Composition and stage dynamics of mitochondrial complexes in Plasmodium falciparum.
Felix Evers,Alfredo Cabrera-Orefice,Dei M. Elurbe,Mariska Kea-te Lindert,Sylwia D. Boltryk,Sylwia D. Boltryk,Till S. Voss,Till S. Voss,Martijn A. Huynen,Ulrich Brandt,Ulrich Brandt,Taco W. A. Kooij +11 more
TL;DR: This article applied complexome profiling to map the inventory of protein complexes across the pathogenic asexual blood stages and the transmissible gametocyte stages of Plasmodium falciparum and found that respiratory chain complex components and linked metabolic pathways are up to 40 times more prevalent in gametocytes, while glycolytic enzymes are substantially reduced.
Complexome Profiling—Exploring Mitochondrial Protein Complexes in Health and Disease
Alfredo Cabrera-Orefice,Alisa Ya. Potter,Felix Evers,Johannes F. Hevler,Sergio Guerrero-Castillo +4 more
TL;DR: The major findings obtained by complexome profiling are summarized; its advantages and current limitations are emphasized; multiple examples on how this tool could be applied to further investigate pathophysiological mechanisms are discussed and comment on the latest advances and opportunity areas to keep developing this methodology.
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Detailing organelle division and segregation in Plasmodium falciparum
Julie M. J. Verhoef,Cas Boshoven,Felix Evers,Laura J. Akkerman,Barend C.A. Gijsbrechts,Marga van de Vegte‑Bolmer,Geert-Jan van Gemert,Akhil B. Vaidya,Taco W. A. Kooij +8 more
TL;DR: A new reporter parasite line that allows visualization of the mitochondrion in blood- and mosquito stages is developed and observations form the foundation for a new detailed model of mitochondrial and apicoplast division and segregation during P. falciparum schizogony.
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WITHDRAWN: Plasmodium falciparum stomatin-like protein forms a putative complex with a metalloprotease in distinct mitochondrial loci
Julie M. J. Verhoef,Ezra T. Bekkering,Cas Boshoven,Megan Hannon,Felix Evers,Nicholas I Proellochs,Cornelia G. Spruijt,Taco W. A. Kooij +7 more