Visual contrast sensitivity could be an early marker of diabetic retinopathy.

Introduction: Diabetic macular edema (DME) is the most common cause of decreased vision in diabetic retinopathy (DR) and its detection needs equipment and skills. Optical coherence tomography (OCT) is an objective technique that can measure retinal morphologic characteristic which help improving diagnosis and treatment. Aims: This study was conducted to evaluate the role of OCT macula in the screening for DME in patients with diabetes by comparing it to clinical funduscopy in addition to assessing the relationship between central macular thickness (CMT) as measured by OCT macula and the visual acuity of patient. Settings and Design: A retrospective study was done at Sidi Hussein Health center/Benghazi in the period between 2014 and 2017. Subjects and Methods: The data of 393 (786 eyes) patients with diabetes (type II) were reviewed. Cases characteristics records were extracted in addition to fundus examination records (done by noncontact +90-diopter lens). The records of OCT (CMT) were evaluated for agreement with the subjective fundus examination and in relation to other measures. Data were presented as frequencies and the statistical analyses were performed using Statistical Package for the Social Science (Windows version 17.0; SPSS Inc., USA). Results: Around 537 eyes (82%) of eyes with mild DME as diagnosed by OCT were having no DR when examined subjectively. With OCT, it was found that 555 eyes (85%) with mild DME were having good visual acuity (logarithm of the minimum angle of resolution 0.3 and less). About 10 eyes (71%) having severe DME were having duration of diabetes of 10–20 years. Conclusions: OCT is a noninvasive method that can objectively detect and quantify early DME before it affects the vision of patients and it is strongly recommended that this should be the technique of choice for detecting and screening of DME in Libyan patients.

Effect of diabetes on central macular thickness quantitatively measured using optical coherence tomography at Sidi-Hussein Health Center, Benghazi, Libya

To assess central macular thickness (CMT) in diabetics with or without diabetic retinopathy (DR) and compare it with various clinical grades of DR. All patients attending the ophthalmic OPD fulfilling the inclusion and met no exclusion criteria were enrolled in this study. All eyes underwent comprehensive and standardized ophthalmic examination. The CMT was measured using spectral domain optical coherence tomography using Cirrus HD OCT Model 500. The mean CMT in cases is significantly greater than controls. It is also significantly greater in diabetics with DR as compared to diabetics without DR and it significantly varies with various grades of DR. The mean CMT is also increased in patients with diabetic macular edema (DME) and panretinal photocoagulation (PRP) untreated DR as compared to diabetics without DME and PRP treated DR respectively. Central macular thickness can be used as an indicator to monitor individuals with diabetes as it increased in diabetics and the presence of macular edema decreased in PRP treated eyes. It also varies with various grades of DR. 

pdf/the-relationship-of-central-macular-thickness-with-clinical-4qfzt4n7gd.pdf

The relationship of central macular thickness with clinical grades of diabetic retinopathy

http://www.aimdrjournal.com/pdf/vol3Issue2/OT1_OA_V3N2.pdf

Central Macular Thickness in Diabetic Retinopathy- A Comparative Study

A Prospective Comparative Study of Efficacy of Topical Anti – Glaucoma Drugs in Primary Open Angle Glaucoma

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Central Macular Thickness in Diabetic Retinopathy- A Comparative Study

A Prospective Comparative Study of Efficacy of Topical Anti – Glaucoma Drugs in Primary Open Angle Glaucoma