Fang Wei
6 Papers
3 Citations
Fang Wei is an academic researcher. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 1, co-authored 3 publications.
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Papers
Anticoagulants Enhance Molecular and Cellular Immunotherapy of Cancer by Improving Tumor Microcirculation Structure and Function and Redistributing Tumor Infiltrates.
Fang Wei,Yuling Su,Yibo Quan,Xiaojia Li,Qi Zou,Liuxi Zhang,Shu Li,Mengmeng Jiang,Guohuan Lin,Ping Liang,Jie He,Keping Xie +11 more
TL;DR: In this article , the authors investigated therapeutic effects and underlying mechanisms of anticoagulants on immunotherapy in pancreatic ductal adenocarcinoma (PDA) and found that combined treatment of heparin and ACT or anti-PD1 produced synergistic antitumor effects, which were at least in part through tumor vascular normalization.
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Low molecular weight heparin synergistically enhances the efficacy of adoptive and anti-PD-1-based immunotherapy by increasing lymphocyte infiltration in colorectal cancer
TL;DR: LMWH could enhance ACT and ICIs-based immunotherapy by increasing lymphocyte infiltration into tumors, especially cytotoxic CD8+ T cells.
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Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma.
Tiansuo Zhao,Tingting Jiang,Xiaojia Li,Shaofei Chang,Qihui Sun,Fanyang Kong,Xiangyu Kong,Fang Wei,Jie He,Jihui Hao,Keping Xie +10 more
TL;DR: Therefore, crosstalk and integration of hypoxia- and hypoglycemia-responsive signaling critically impact PDA metabolic reprogramming and therapeutic resistance.
5
Clinical significance of pancreatic ductal metaplasia
TL;DR: Functional identification of the cellular and molecular events driving senescence and apoptosis in PDM and its progression would help not only to restrict the development of PDM into PanIN/PDAC, but may also facilitate pancreatic regeneration.
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High FAM111B expression predicts aggressive clinicopathologic features and poor prognosis in ovarian cancer.
TL;DR: In this paper , the significance of FAM111B expression was verified bioinformatically using the Gene Expression Omnibus database, and correlations between FAM 111B expression and clinicopathologic features were investigated by the Clu-square test.